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    ECM1 Ecm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851240, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ECM1
    Official Full Name
    Ecm1p
    Primary source
    SGD:S000000055
    Locus tag
    YAL059W
    See related
    AllianceGenome:SGD:S000000055; FungiDB:YAL059W; VEuPathDB:YAL059W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ribosomal large subunit export from nucleus. Located in nucleolus. Part of preribosome, large subunit precursor. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ECM1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_001133.9 (36509..37147)

    Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene putative dehydrogenase BDH2 Neighboring gene (R,R)-butanediol dehydrogenase Neighboring gene calnexin Neighboring gene Gpb2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001133.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ecm11 is located in the cell nucleus throughout mitosis. Comino A, et al. Pflugers Arch, 2001. PMID 11678331
    2. Bcp1 Is the Nuclear Chaperone of Rpl23 in Saccharomyces cerevisiae. Ting YH, et al. J Biol Chem, 2017 Jan 13. PMID 27913624, Free PMC Article
    3. Coupling protein complex analysis to peptide based proteomics. Gao Q, et al. J Chromatogr A, 2010 Dec 3. PMID 21036361
    4. A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis. Albanèse V, et al. J Cell Biol, 2010 Apr 5. PMID 20368619, Free PMC Article
    5. Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Cooney I, et al. Science, 2019 Aug 2. PMID 31249134, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit export from nucleus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of preribosome, large subunit precursor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ecm1p
    NP_009342.2
    • Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001133.9 Reference assembly

      Range
      36509..37147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178201.2 → NP_009342.2  TPA: Ecm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009342.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPG0, E9P8V4, P39715
      UniProtKB/TrEMBL
      G2W8H4, N1P9T5
      Conserved Domains (1) summary
      pfam09135
      Location:31 → 152
      Alb1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39715.2

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