Cep162 centrosomal protein 162 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cep162provided by MGI
Official Full Name: centrosomal protein 162provided by MGI
Primary source: MGI:MGI:1925343
See related: Ensembl:ENSMUSG00000056919 AllianceGenome:MGI:1925343
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: mKIAA1009; 4922501C03Rik
Summary: Predicted to be involved in cilium assembly. Predicted to be located in centrosome and cytosol. Predicted to be active in microtubule cytoskeleton and nucleoplasm. Orthologous to human CEP162 (centrosomal protein 162). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 3.6), CNS E14 (RPKM 2.6) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 E3.1; 9 46.78 cM

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (87071626..87137589, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (87189573..87255536, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Chemically induced (ENU) (3)
Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D10Mit157.2 (e-PCR), detects polymorphism
- UniSTS:126061

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in axonemal microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
is_active_in centriolar satellite	IBA Inferred from Biological aspect of Ancestor more info
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in spindle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: centrosomal protein of 162 kDa

Names: protein QN1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199316.2 → NP_955020.2 centrosomal protein of 162 kDa

See identical proteins and their annotated locations for NP_955020.2

Status: VALIDATED

Source sequence(s)

AI049385, AK129260, AK135482, BB413728, BC028799, BF465741, BF721651, CB246096, CK639077, CN456181

Consensus CDS

CCDS52879.1

UniProtKB/Swiss-Prot

B9EKN3, Q6P262, Q6ZQ06

UniProtKB/TrEMBL

B9EKT8

Related

ENSMUSP00000091319.5, ENSMUST00000093802.6

Conserved Domains (1) summary

COG1196
Location:617 → 1301

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000075.7 Reference GRCm39 C57BL/6J

Range

87071626..87137589 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030244438.1 → XP_030100298.1 centrosomal protein of 162 kDa isoform X1

UniProtKB/TrEMBL

B9EKT8

Conserved Domains (1) summary

TIGR02168
Location:422 → 1165

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_006511263.4 → XP_006511326.1 centrosomal protein of 162 kDa isoform X2

Conserved Domains (1) summary

TIGR02168
Location:31 → 774

SMC_prok_B; chromosome segregation protein SMC, common bacterial type
XM_006511264.1 → XP_006511327.1 centrosomal protein of 162 kDa isoform X3

Conserved Domains (1) summary

pfam06785
Location:610 → 731

UPF0242; Uncharacterized protein family (UPF0242)