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    RPS4A ribosomal 40S subunit protein S4A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853610, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS4A
    Official Full Name
    ribosomal 40S subunit protein S4A
    Primary source
    SGD:S000003906
    Locus tag
    YJR145C
    See related
    AllianceGenome:SGD:S000003906; FungiDB:YJR145C; VEuPathDB:YJR145C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Predicted to be involved in translation. Located in cytoplasm. Part of cytosolic small ribosomal subunit. Orthologous to human RPS4X (ribosomal protein S4 X-linked); RPS4Y1 (ribosomal protein S4 Y-linked 1); and RPS4Y2 (ribosomal protein S4 Y-linked 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS4A in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    2
    Sequence:
    Chromosome: X; NC_001142.9 (702027..703068, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate-mannose-protein mannosyltransferase Neighboring gene Mgm101p Neighboring gene uncharacterized protein Neighboring gene Hms2p Neighboring gene branched-chain-amino-acid transaminase BAT2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The yeast ribosomal protein S7 and its genes. Synetos D, et al. J Biol Chem, 1992 Feb 15. PMID 1737755
    2. Secondary structure is required for 3' splice site recognition in yeast. Gahura O, et al. Nucleic Acids Res, 2011 Dec. PMID 21893588, Free PMC Article
    3. Saccharomyces cerevisiae coordinates accumulation of yeast ribosomal proteins by modulating mRNA splicing, translational initiation, and protein turnover. Warner JR, et al. Mol Cell Biol, 1985 Jun. PMID 3897837, Free PMC Article
    4. Transcription mediated insulation and interference direct gene cluster expression switches. Nguyen T, et al. Elife, 2014 Nov 19. PMID 25407679, Free PMC Article
    5. The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in Saccharomyces cerevisiae. Wu Y, et al. FEMS Yeast Res, 2016 May. PMID 26975390

    See all (124) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular membraneless organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S4A
    NP_012679.3
    • Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; homologous to mammalian ribosomal protein S4, no bacterial homolog; RPS4A has a paralog, RPS4B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      702027..703068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181803.3 → NP_012679.3  TPA: ribosomal 40S subunit protein S4A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012679.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLF2, P05753, P0CX35, P0CX36
      UniProtKB/TrEMBL
      A6ZQA2, B3LQM5, C8ZA04, G2WFS7, N1P4X8
      Conserved Domains (1) summary
      PLN00036
      Location:1 → 259
      PLN00036; 40S ribosomal protein S4; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX35.1
    P0CX36.1

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