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    STB4 Stb4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855033, updated on 9-Dec-2024

    Summary

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    Official Symbol
    STB4
    Official Full Name
    Stb4p
    Primary source
    SGD:S000004621
    Locus tag
    YMR019W
    See related
    AllianceGenome:SGD:S000004621; FungiDB:YMR019W; VEuPathDB:YMR019W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription and regulation of transcription by RNA polymerase II. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See STB4 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (312156..315005)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Spo20p Neighboring gene Pex9p Neighboring gene polyamine oxidase Neighboring gene Mac1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences. Ward LD, et al. Bioinformatics, 2008 Jul 1. PMID 18586710, Free PMC Article
    2. Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Kasten MM, et al. Mol Gen Genet, 1997 Oct. PMID 9393435
    3. Transcriptional regulatory code of a eukaryotic genome. Harbison CT, et al. Nature, 2004 Sep 2. PMID 15343339, Free PMC Article
    4. Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Yang Y, et al. Cell Res, 2010 Nov. PMID 20975739
    5. Phenotypic analysis of genes encoding yeast zinc cluster proteins. Akache B, et al. Nucleic Acids Res, 2001 May 15. PMID 11353088, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Stb4p
    NP_013732.1
    • Putative transcription factor; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters; binds Sin3p in a two-hybrid assay

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      312156..315005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182515.1 → NP_013732.1  TPA: Stb4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013732.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZJ3, P50104
      UniProtKB/TrEMBL
      C7GLA0
      Conserved Domains (2) summary
      smart00066
      Location:82 → 122
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
      pfam04082
      Location:401 → 661
      Fungal_trans; Fungal specific transcription factor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50104.1

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