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    FYV6 Fyv6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855589, updated on 17-Dec-2024

    Summary

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    Official Symbol
    FYV6
    Official Full Name
    Fyv6p
    Primary source
    SGD:S000005077
    Locus tag
    YNL133C
    See related
    AllianceGenome:SGD:S000005077; FungiDB:YNL133C; VEuPathDB:YNL133C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in double-strand break repair via nonhomologous end joining. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See FYV6 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (374171..374692, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase FPR1 Neighboring gene uncharacterized protein Neighboring gene tRNA-Phe Neighboring gene ribosome biosynthesis protein KRE33

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical and genetic evidence supports Fyv6 as a second-step splicing factor in Saccharomyces cerevisiae. Lipinski KA, et al. RNA, 2023 Nov. PMID 37625852, Free PMC Article
    2. Identification of pathways controlling DNA damage induced mutation in Saccharomyces cerevisiae. Lis ET, et al. DNA Repair (Amst), 2008 May 3. PMID 18400565, Free PMC Article
    3. A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio. Wilson TE. Genetics, 2002 Oct. PMID 12399380, Free PMC Article
    4. A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Pagé N, et al. Genetics, 2003 Mar. PMID 12663529, Free PMC Article
    5. Perturbations of Transcription and Gene Expression-Associated Processes Alter Distribution of Cell Size Values in Saccharomyces cerevisiae. Maitra N, et al. G3 (Bethesda), 2019 Jan 9. PMID 30463882, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Biochemical and genetic evidence supports Fyv6 as a second-step splicing factor in Saccharomyces cerevisiae.
      Title: Biochemical and genetic evidence supports Fyv6 as a second-step splicing factor in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in double-strand break repair via nonhomologous end joining IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fyv6p
    NP_014266.3
    • Splicing factor, structural and functional homolog of human FAM192A; plays structural role in intermediate spliceosomal C* complex, which executes exon ligation; required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      374171..374692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182971.3 → NP_014266.3  TPA: Fyv6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014266.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W149, P53913
      UniProtKB/TrEMBL
      A6ZRV0, B3LNZ0, C8ZG97, N1NWI3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53913.1

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