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    YRF1-8 Y' element ATP-dependent helicase protein 1 copy 8 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854577, updated on 4-Jan-2025

    Summary

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    Official Symbol
    YRF1-8
    Official Full Name
    Y' element ATP-dependent helicase protein 1 copy 8
    Primary source
    SGD:S000007526
    Locus tag
    YOR396W
    See related
    AllianceGenome:SGD:S000007526; FungiDB:YOR396W; VEuPathDB:YOR396W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable helicase activity. Predicted to be involved in chromatin looping; chromatin remodeling; and chromosome organization. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See YRF1-8 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (1085473..1090863)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene seripauperin PAU21 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. Yamada M, et al. J Biol Chem, 1998 Dec 11. PMID 9837911
    2. The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Bareth B, et al. Mol Cell Biol, 2013 Oct. PMID 23979592, Free PMC Article
    3. TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity. Chymkowitch P, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096404, Free PMC Article
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Dujon B, et al. Nature, 1997 May 29. PMID 9169874
    5. Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Scherrer T, et al. Genome Biol, 2011. PMID 21232131, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables double-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables forked DNA-dependent helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables four-way junction helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in telomere maintenance via recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Y' element ATP-dependent helicase protein 1 copy 8
    NP_061495.4
    • One of several telomeric Y' element-encoded DNA helicases; known as Y'-Help1 (Y'-HELicase Protein 1)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      1085473..1090863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184447.3 → NP_061495.4  TPA: Y' element ATP-dependent helicase protein 1 copy 8 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_061495.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTG2, O94087, P0CX20, P0CX21, P0CX22, P24088, P24089, Q53WX0, Q99313
      Conserved Domains (2) summary
      COG0513
      Location:736 → 1225
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      pfam11603
      Location:13 → 88
      Sir1; Regulatory protein Sir1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX20.1
    P0CX21.1
    P0CX22.1

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