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    INO1 inositol-3-phosphate synthase INO1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853288, updated on 9-Dec-2024

    Summary

    Official Symbol
    INO1
    Official Full Name
    inositol-3-phosphate synthase INO1
    Primary source
    SGD:S000003689
    Locus tag
    YJL153C
    See related
    AllianceGenome:SGD:S000003689; FungiDB:YJL153C; VEuPathDB:YJL153C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    APR1
    Summary
    Enables inositol-3-phosphate synthase activity. Involved in inositol biosynthetic process. Located in cytoplasm. Orthologous to human ISYNA1 (inositol-3-phosphate synthase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See INO1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (134332..135933, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene fructose-2,6-bisphosphatase Neighboring gene retromer subunit VPS35 Neighboring gene Sna3p Neighboring gene SCF ubiquitin ligase complex subunit DAS1

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables inositol-3-phosphate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables inositol-3-phosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables inositol-3-phosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in inositol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inositol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in inositol biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    inositol-3-phosphate synthase INO1
    NP_012382.2
    • Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      134332..135933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181586.1NP_012382.2  TPA: inositol-3-phosphate synthase INO1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012382.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW34, P11986
      UniProtKB/TrEMBL
      A6ZQH9, B3LPW8, C7GPY0, C8ZB67, N1P1Z0
      Conserved Domains (1) summary
      pfam07994
      Location:66515
      NAD_binding_5; Myo-inositol-1-phosphate synthase