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    PBI1 Pbi1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855856, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PBI1
    Official Full Name
    Pbi1p
    Primary source
    SGD:S000006193
    Locus tag
    YPL272C
    See related
    AllianceGenome:SGD:S000006193; FungiDB:YPL272C; VEuPathDB:YPL272C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable N-acetyltransferase activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PBI1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (26611..28164, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene bifunctional polyamine/amino acid permease SAM3 Neighboring gene S-adenosylmethionine-homocysteine S-methyltransferase SAM4 Neighboring gene F1F0 ATP synthase subunit epsilon Neighboring gene ATP-binding cassette permease MDL2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosphatidylserine-induced dissociation of the heterodimeric PstB2p/Pbi1p complex in yeast phosphatidylserine trafficking system. Cho HJ, et al. Biochem Biophys Res Commun, 2019 Sep 17. PMID 31351588
    2. Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. Agarwal AK, et al. J Biol Chem, 2003 Sep 12. PMID 12824174
    3. An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae. Riekhof WR, et al. J Biol Chem, 2014 Feb 28. PMID 24366873, Free PMC Article
    4. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. Atencio D, et al. G3 (Bethesda), 2014 Mar 20. PMID 24470217, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Bussey H, et al. Nature, 1997 May 29. PMID 9169875

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PstB2p forms a homodimer but exists as a 1:1 heterodimer in the presence of Pbi1p. Phosphatidylserine binding to PstB2p triggers the dissociation of the PstB2p-Pbi1p complex.
      Title: Phosphatidylserine-induced dissociation of the heterodimeric PstB2p/Pbi1p complex in yeast phosphatidylserine trafficking system.
    2. model predicts that this process involves an acceptor membrane complex containing the C2 domains of Psd2p, PstB2p, and Pbi1p that ligate to Scs2p and phosphatidic acid present in the donor membrane
      Title: An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Pbi1p
    NP_015051.1
    • hypothetical protein; gene expression induced in response to ketoconazole; YPL272C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      26611..28164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184086.1 → NP_015051.1  TPA: Pbi1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015051.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W398, Q08984
      UniProtKB/TrEMBL
      B3LKG1, B5VSR7, C7GSH2, C8ZIA7
      Conserved Domains (1) summary
      cl23853
      Location:32 → 279
      Condensation; Condensation domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08984.1

    Gene LinkOut

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