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    2-aminoadipate transaminase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856896, updated on 9-Dec-2024

    Summary

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    Official Full Name
    2-aminoadipate transaminase
    Primary source
    SGD:S000000954
    Locus tag
    YER152C
    See related
    AllianceGenome:SGD:S000000954; FungiDB:YER152C; VEuPathDB:YER152C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables 2-aminoadipate transaminase activity. Predicted to be involved in biosynthetic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (472657..473988, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene tRNA-Val Neighboring gene mRNA-binding ubiquitin-specific protease UBP3 Neighboring gene Pet122p Neighboring gene membrane insertase OXA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily. Iraqui I, et al. Mol Gen Genet, 1998 Jan. PMID 9491083
    2. The automation of science. King RD, et al. Science, 2009 Apr 3. PMID 19342587
    3. On the formalization and reuse of scientific research. King RD, et al. J R Soc Interface, 2011 Oct 7. PMID 21490004, Free PMC Article
    4. Kynurenine aminotransferase activity of Aro8/Aro9 engage tryptophan degradation by producing kynurenic acid in Saccharomyces cerevisiae. Ohashi K, et al. Sci Rep, 2017 Sep 22. PMID 28939805, Free PMC Article
    5. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Hesselberth JR, et al. Genome Biol, 2006. PMID 16606443, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 2-aminoadipate transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 2-aminoadipate transaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    2-aminoadipate transaminase
    NP_011079.3
    • Protein with 2-aminoadipate transaminase activity; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      472657..473988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179042.3 → NP_011079.3  TPA: 2-aminoadipate transaminase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011079.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM59, P10356
      UniProtKB/TrEMBL
      A6ZRA9, B3LRR5, B5VHT1, C7GQ44, C8Z7H4
      Conserved Domains (1) summary
      COG1167
      Location:1 → 436
      ARO8; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10356.2

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