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    F53B6.5 Peptidase_M24 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 353384, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F53B6.5
    Official Full Name
    Peptidase_M24 domain-containing protein
    Primary source
    WormBase:WBGene00009960
    Locus tag
    CELE_F53B6.5
    See related
    AllianceGenome:WB:WBGene00009960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Orthologous to human METAP2 (methionyl aminopeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F53B6.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (8950448..8951053)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene Major sperm protein Neighboring gene O-fucosyltransferase family protein Neighboring gene Elf-1_N domain-containing protein Neighboring gene tRNA-Lys Neighboring gene ncRNA Neighboring gene ZP domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables aminopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloexopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Peptidase_M24 domain-containing protein
    NP_492408.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8950448..8951053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060007.2 → NP_492408.2  Peptidase_M24 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492408.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90883
      Conserved Domains (1) summary
      cl00279
      Location:37 → 151
      APP_MetAP; A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity ...
    Nucleotide Protein
    Heading Accession and Version

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