Gdpgp1 GDP-D-glucose phosphorylase 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gdpgp1provided by MGI
Official Full Name: GDP-D-glucose phosphorylase 1provided by MGI
Primary source: MGI:MGI:2443429
See related: Ensembl:ENSMUSG00000050973 AllianceGenome:MGI:2443429
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D330012F22Rik
Summary: Predicted to enable GDP-D-glucose phosphorylase activity. Predicted to be involved in glucose metabolic process. Predicted to be active in cytoplasm. Orthologous to human GDPGP1 (GDP-D-glucose phosphorylase 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in colon adult (RPKM 2.7), large intestine adult (RPKM 2.1) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 D2; 7 45.56 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (79882641..79891168)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (80232893..80241420)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
Title: The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

05.MMHAP58FLB2.seq (e-PCR)
- UniSTS:122820

D5Mit392.1 (e-PCR), detects polymorphism
- UniSTS:130544

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables GDP-D-glucose phosphorylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GDP-D-glucose phosphorylase activity	ISO Inferred from Sequence Orthology more info
enables GDP-D-glucose phosphorylase activity	ISS Inferred from Sequence or Structural Similarity more info
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glucose metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glucose metabolic process	ISO Inferred from Sequence Orthology more info
involved_in glucose metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: GDP-D-glucose phosphorylase 1

Names: GDP-D-glucose phosphorylase C15orf58 homolog

NP_848867.2

EC 2.7.7.78

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.