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    Garin4 golgi associated RAB2 interactor family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 619288, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Garin4provided by MGI
    Official Full Name
    golgi associated RAB2 interactor family member 4provided by MGI
    Primary source
    MGI:MGI:3588202
    See related
    Ensembl:ENSMUSG00000091017 AllianceGenome:MGI:3588202
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam71a; GARI-L4; 4933417M04Rik
    Summary
    Acts upstream of or within cell morphogenesis. Is active in sperm head. Orthologous to human GARIN4 (golgi associated RAB2 interactor family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human all
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    Genomic context

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    See Garin4 in Genome Data Viewer
    Location:
    1 H6; 1 96.28 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (190894781..190897014, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (191162584..191164817, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31640 Neighboring gene STARR-seq mESC enhancer starr_03427 Neighboring gene predicted gene, 31696 Neighboring gene activating transcription factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E4405 Neighboring gene STARR-seq mESC enhancer starr_03429 Neighboring gene STARR-positive B cell enhancer ABC_E2027 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:193017813-193017996 Neighboring gene STARR-positive B cell enhancer mm9_chr1:193021775-193022076 Neighboring gene RIKEN cDNA D730003I15 gene Neighboring gene STARR-positive B cell enhancer ABC_E1578

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. Wang H, et al. PLoS Genet, 2024 Jun. PMID 38935810, Free PMC Article
    2. Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity. Fukuda M, et al. Mol Cell Proteomics, 2008 Jun. PMID 18256213
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in sperm head IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Golgi-associated RAB2 interactor protein 4
    Names
    Golgi-associated Rab2B interactor-like 4
    family with sequence similarity 71, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109759.1 → NP_001103229.1  Golgi-associated RAB2 interactor protein 4

      See identical proteins and their annotated locations for NP_001103229.1

      Status: VALIDATED

      Source sequence(s)
      AC138229, AK133412
      Consensus CDS
      CCDS48487.1
      UniProtKB/TrEMBL
      B7XG49
      Related
      ENSMUSP00000127945.2, ENSMUST00000171798.2
      Conserved Domains (1) summary
      pfam12480
      Location:122 → 193
      DUF3699; Protein of unknown function (DUF3699)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      190894781..190897014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_006991.1: Suppressed sequence

      Description
      NG_006991.1: This RefSeq was permanantly suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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