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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851550, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000002170
    Locus tag
    YDL012C
    See related
    AllianceGenome:SGD:S000002170; FungiDB:YDL012C; VEuPathDB:YDL012C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (431108..431517, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene rRNA methyltransferase NOP1 Neighboring gene SUMO-targeted ubiquitin ligase complex subunit SLX5 Neighboring gene glutathione-disulfide reductase GRX6 Neighboring gene uncharacterized protein Neighboring gene anaphase promoting complex subunit 11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Global investigation of protein-protein interactions in yeast Saccharomyces cerevisiae using re-occurring short polypeptide sequences. Pitre S, et al. Nucleic Acids Res, 2008 Aug. PMID 18586826, Free PMC Article
    2. Disruption and functional analysis of seven ORFs on chromosome IV: YDL057w, YDL012c, YDL010w, YDL009c, YDL008w (APC11), YDL005c (MED2) and YDL003w (MCD1). Smith KN, et al. Yeast, 1999 Sep 15. PMID 10487928
    3. CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. Venancio TM, et al. Bioinformatics, 2010 Jan 15. PMID 19933165, Free PMC Article
    4. Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. Beilharz T, et al. J Biol Chem, 2003 Mar 7. PMID 12514182
    5. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Gupta R, et al. Mol Syst Biol, 2007. PMID 17551511, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cellular bud HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_010272.1
    • Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      431108..431517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180071.1 → NP_010272.1  TPA: uncharacterized protein YDL012C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010272.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRX7, Q12489
      UniProtKB/TrEMBL
      A6ZXV6, B3LGR9, C7GW66, C8Z4Q7, G2WCE3, N1PAB1
      Conserved Domains (1) summary
      pfam12734
      Location:75 → 107
      CYSTM; Cysteine-rich TM module stress tolerance
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12489.1

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