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    Fundc2b FUN14 domain containing 2B [ Mus musculus (house mouse) ]

    Gene ID: 73297, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fundc2bprovided by MGI
    Official Full Name
    FUN14 domain containing 2Bprovided by MGI
    Primary source
    MGI:MGI:1920547
    See related
    Ensembl:ENSMUSG00000074619 AllianceGenome:MGI:1920547
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700034I23Rik
    Summary
    Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in autophagy of mitochondrion and intracellular triglyceride homeostasis. Located in mitochondrion. Orthologous to human FUNDC2 (FUN14 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Fundc2b in Genome Data Viewer
    Location:
    3 B; 3 19.58 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (40854631..40856936, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (40900196..40902501, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene 2011 Neighboring gene FUN14 domain containing 2 pseudogene Neighboring gene RIKEN cDNA 6430590A07 gene Neighboring gene abhydrolase domain containing 18 Neighboring gene STARR-positive B cell enhancer ABC_E7910 Neighboring gene STARR-seq mESC enhancer starr_07475 Neighboring gene La ribonucleoprotein 1B Neighboring gene predicted gene, 22043 Neighboring gene predicted gene 42437

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Clone Names

    • MGC143484

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular triglyceride homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    1700034I23Rik
    Names
    FUN14 domain containing 2 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028494.3NP_082770.1  1700034I23Rik

      Status: VALIDATED

      Source sequence(s)
      AC160757
      UniProtKB/TrEMBL
      Q8C5W7, Q9D9Q3
      Related
      ENSMUSP00000141045.2, ENSMUST00000099123.5
      Conserved Domains (1) summary
      pfam04930
      Location:82168
      FUN14; FUN14 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      40854631..40856936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_045380.1: Suppressed sequence

      Description
      NR_045380.1: This RefSeq was removed because it is now thought that this gene does encode a protein.