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    Ppp1r14bl protein phosphatase 1, regulatory inhibitor subunit 14B like [ Mus musculus (house mouse) ]

    Gene ID: 66755, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ppp1r14blprovided by MGI
    Official Full Name
    protein phosphatase 1, regulatory inhibitor subunit 14B likeprovided by MGI
    Primary source
    MGI:MGI:1914005
    See related
    Ensembl:ENSMUSG00000073730 AllianceGenome:MGI:1914005
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933415F23Rik
    Summary
    Predicted to enable protein serine/threonine phosphatase inhibitor activity. Acts upstream of or within innate immune response. Orthologous to human PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Ppp1r14bl in Genome Data Viewer
    Location:
    1 A5; 1 9.35 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (23139554..23141334, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (23100473..23102253, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_00424 Neighboring gene predicted gene 7759 Neighboring gene STARR-seq mESC enhancer starr_00425 Neighboring gene predicted gene 7761 Neighboring gene STARR-seq mESC enhancer starr_00426 Neighboring gene STARR-seq mESC enhancer starr_00427 Neighboring gene STARR-seq mESC enhancer starr_00428 Neighboring gene 4.5s RNA, pseudogene 4 Neighboring gene predicted gene, 30442

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 1, regulatory (inhibitor) subunit 14B-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025746.2NP_080022.2  protein phosphatase 1, regulatory (inhibitor) subunit 14B-like

      See identical proteins and their annotated locations for NP_080022.2

      Status: VALIDATED

      Source sequence(s)
      AK016819, AV040646, BC115556
      Consensus CDS
      CCDS48231.1
      UniProtKB/TrEMBL
      Q14BX6
      Related
      ENSMUSP00000072920.6, ENSMUST00000073179.6
      Conserved Domains (1) summary
      pfam05361
      Location:23146
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      23139554..23141334 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)