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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001359083.1 → NP_001346012.1 mannan-binding lectin serine protease 1 isoform 1 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC154571, AC163612
- Consensus CDS
-
CCDS88904.1
- Related
- ENSMUSP00000155665.2, ENSMUST00000229619.2
- Conserved Domains (6) summary
-
- cd00033
Location:306 → 368
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- smart00020
Location:454 → 715
- Tryp_SPc; Trypsin-like serine protease
- cd00041
Location:33 → 142
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- pfam00431
Location:190 → 299
- CUB; CUB domain
- pfam00084
Location:372 → 437
- Sushi; Sushi repeat (SCR repeat)
- pfam14670
Location:158 → 186
- FXa_inhibition; Coagulation Factor Xa inhibitory site
-
NM_008555.3 → NP_032581.2 mannan-binding lectin serine protease 1 isoform 2 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AC154571, AC163612
- Consensus CDS
-
CCDS37303.1
- UniProtKB/Swiss-Prot
- A2RRH8, A2RRH9, P98064, Q8CD27, Q8CIR8, Q920S0
- Related
- ENSMUSP00000087327.6, ENSMUST00000089883.7
- Conserved Domains (6) summary
-
- cd00033
Location:306 → 368
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- smart00020
Location:453 → 696
- Tryp_SPc; Trypsin-like serine protease
- cd00041
Location:33 → 142
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- cd00190
Location:454 → 699
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam00431
Location:190 → 299
- CUB; CUB domain
- pfam14670
Location:158 → 186
- FXa_inhibition; Coagulation Factor Xa inhibitory site
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000082.7 Reference GRCm39 C57BL/6J
- Range
-
23261778..23340127 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_036159811.1 → XP_036015704.1 mannan-binding lectin serine protease 1 isoform X4
- Conserved Domains (2) summary
-
- cd00190
Location:87 → 332
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam00084
Location:5 → 70
- Sushi; Sushi repeat (SCR repeat)
-
XM_036159809.1 → XP_036015702.1 mannan-binding lectin serine protease 1 isoform X1
- Conserved Domains (6) summary
-
- cd00033
Location:306 → 368
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- PHA02639
Location:305 → 438
- PHA02639; EEV host range protein; Provisional
- cd00041
Location:33 → 142
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- cd00190
Location:454 → 699
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam00431
Location:190 → 299
- CUB; CUB domain
- pfam14670
Location:158 → 186
- FXa_inhibition; Coagulation Factor Xa inhibitory site
-
XM_036159810.1 → XP_036015703.1 mannan-binding lectin serine protease 1 isoform X2
- Conserved Domains (6) summary
-
- cd00033
Location:306 → 368
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- PHA02639
Location:305 → 438
- PHA02639; EEV host range protein; Provisional
- cd00041
Location:33 → 142
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- cd00190
Location:454 → 699
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam00431
Location:190 → 299
- CUB; CUB domain
- pfam14670
Location:158 → 186
- FXa_inhibition; Coagulation Factor Xa inhibitory site
-
XM_006521829.5 → XP_006521892.1 mannan-binding lectin serine protease 1 isoform X3
- UniProtKB/TrEMBL
-
A0A2R8VHR3
- Related
- ENSMUSP00000155343.2, ENSMUST00000230040.2
- Conserved Domains (4) summary
-
- cd00033
Location:306 → 368
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- cd00041
Location:33 → 142
- CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
- pfam00431
Location:190 → 299
- CUB; CUB domain
- pfam14670
Location:158 → 186
- FXa_inhibition; Coagulation Factor Xa inhibitory site
RNA
-
XR_003951766.2 RNA Sequence