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    Nup155 nucleoporin 155 [ Mus musculus (house mouse) ]

    Gene ID: 170762, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nup155provided by MGI
    Official Full Name
    nucleoporin 155provided by MGI
    Primary source
    MGI:MGI:2181182
    See related
    Ensembl:ENSMUSG00000022142 AllianceGenome:MGI:2181182
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0791; D930027M19Rik
    Summary
    Predicted to be a structural constituent of nuclear pore. Acts upstream of or within with a positive effect on miRNA processing and protein localization to nucleus. Acts upstream of or within atrial cardiac muscle cell action potential; mRNA export from nucleus; and protein import into nucleus. Located in nuclear envelope. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human NUP155 (nucleoporin 155). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 11.0), limb E14.5 (RPKM 8.9) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Nup155 in Genome Data Viewer
    Location:
    15 A1; 15 3.82 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (8135861..8189343)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (8109263..8159859)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37886 Neighboring gene basic transcription factor 3, pseudogene 16 Neighboring gene WD repeat domain 70 Neighboring gene STARR-seq mESC enhancer starr_37887 Neighboring gene ribosomal protein L19, pseudogene 6 Neighboring gene STARR-positive B cell enhancer mm9_chr15:8047913-8048213 Neighboring gene STARR-seq mESC enhancer starr_37890 Neighboring gene STARR-seq mESC enhancer starr_37891 Neighboring gene STARR-seq mESC enhancer starr_37892 Neighboring gene STARR-seq mESC enhancer starr_37894 Neighboring gene ciliogenesis and planar polarity effector 1 Neighboring gene predicted gene, 46494 Neighboring gene STARR-seq mESC enhancer starr_37895 Neighboring gene predicted gene, 24144

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of nuclear pore inner ring IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup155
    Names
    155 kDa nucleoporin
    nucleoporin Nup155

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133227.3NP_573490.3  nuclear pore complex protein Nup155

      Status: VALIDATED

      Source sequence(s)
      AK086426, AK129217, CO040753, CO433695
      Consensus CDS
      CCDS37034.1
      UniProtKB/Swiss-Prot
      Q99P88
      UniProtKB/TrEMBL
      Q80X48
      Related
      ENSMUSP00000128819.2, ENSMUST00000163765.3
      Conserved Domains (2) summary
      pfam03177
      Location:10081213
      Nucleoporin_C; Non-repetitive/WGA-negative nucleoporin C-terminal
      pfam08801
      Location:77507
      Nucleoporin_N; Nup133 N terminal like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      8135861..8189343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003951358.2 RNA Sequence