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    Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [ Mus musculus (house mouse) ]

    Gene ID: 106952, updated on 9-Dec-2024

    Summary

    Official Symbol
    Arap3provided by MGI
    Official Full Name
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3provided by MGI
    Primary source
    MGI:MGI:2147274
    See related
    Ensembl:ENSMUSG00000024451 AllianceGenome:MGI:2147274
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drag1; Centd3; cnt-d3; E030006K04Rik
    Summary
    This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
    Expression
    Biased expression in lung adult (RPKM 62.4), subcutaneous fat pad adult (RPKM 16.7) and 13 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Arap3 in Genome Data Viewer
    Location:
    18 B3; 18 19.85 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (38105676..38132583, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (37972623..37999531, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene histone deacetylase 3 Neighboring gene FCH and double SH3 domains 1 Neighboring gene RELT-like 2 Neighboring gene microRNA 6981 Neighboring gene microRNA 6980 Neighboring gene predicted gene, 30093 Neighboring gene predicted gene, 41701 Neighboring gene STARR-seq mESC enhancer starr_44342 Neighboring gene predicted gene, 30188 Neighboring gene STARR-seq mESC enhancer starr_44344 Neighboring gene predicted gene, 30142

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (3)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA4097

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-3,4-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ruffle IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
    Names
    ARF-GAP, RHO-GAP, ankyrin repeat and pleckstrin homology domains-containing protein 3
    centaurin, delta 3
    dual-specificity Rho- and Arf-GTPase activating protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205336.2NP_001192265.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC121886, AC129315
      Consensus CDS
      CCDS89225.1
      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Related
      ENSMUSP00000157868.2, ENSMUST00000237272.2
      Conserved Domains (8) summary
      cd04385
      Location:8271002
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:206298
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:313396
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:11311247
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      pfam00169
      Location:205296
      PH; PH domain
      pfam00788
      Location:10351128
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:407523
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:592704
      PH-like; Pleckstrin homology-like domain
    2. NM_139206.3NP_631945.2  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1

      See identical proteins and their annotated locations for NP_631945.2

      Status: REVIEWED

      Source sequence(s)
      AC121886, AC129315
      Consensus CDS
      CCDS29196.1
      UniProtKB/Swiss-Prot
      E9QMK7, Q5DTN4, Q6NVF1, Q8R5G6, Q8R5G7
      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Related
      ENSMUSP00000035662.8, ENSMUST00000042944.9
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14711537
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81311
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9051080
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:284376
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:391474
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12091325
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:484599
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:670782
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11121209
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      38105676..38132583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525492.4XP_006525555.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

      See identical proteins and their annotated locations for XP_006525555.1

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (9) summary
      PLN02983
      Location:13941460
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:3234
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:8281003
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:207299
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:314397
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:11321248
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:407522
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:593705
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:10351132
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    2. XM_006525488.4XP_006525551.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006525551.1

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14721538
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81312
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9061081
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:285377
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:392475
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12101326
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:485600
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:671783
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11131210
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    3. XM_036160919.1XP_036016812.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (9) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      cd04385
      Location:9051080
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:284376
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:391474
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12091325
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:484599
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      NF033838
      Location:81150
      PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form
      cl17171
      Location:670782
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11121209
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    4. XM_006525489.3XP_006525552.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2

      See identical proteins and their annotated locations for XP_006525552.1

      UniProtKB/Swiss-Prot
      E9QMK7, Q5DTN4, Q6NVF1, Q8R5G6, Q8R5G7
      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14711537
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81311
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9051080
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:284376
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:391474
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12091325
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:484599
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:670782
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11121209
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    5. XM_006525491.3XP_006525554.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

      See identical proteins and their annotated locations for XP_006525554.1

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (9) summary
      PLN02983
      Location:13941460
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:3234
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:8281003
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:207299
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:314397
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:11321248
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:407522
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:593705
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:10351132
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    6. XM_006525490.1XP_006525553.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14591525
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81312
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9061081
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:285377
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:392475
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12101326
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:485600
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:671783
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11131210
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    7. XM_006525486.1XP_006525549.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006525549.1

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14721538
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81312
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9061081
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:285377
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:392475
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12101326
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:485600
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:671783
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11131210
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    8. XM_036160921.1XP_036016814.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (9) summary
      PHA03247
      Location:3233
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:8271002
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:206298
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:313396
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:11311247
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:406521
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      NF033838
      Location:372
      PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form
      cl17171
      Location:592704
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:10341131
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    9. XM_030250262.2XP_030106122.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (9) summary
      PLN02983
      Location:13941460
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:3234
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:8281003
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:207299
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:314397
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:11321248
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:407522
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:593705
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:10351132
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    10. XM_006525487.5XP_006525550.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006525550.1

      UniProtKB/TrEMBL
      A0A2X0TVQ3
      Conserved Domains (10) summary
      cd09490
      Location:466
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      PLN02983
      Location:14721538
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
      PHA03247
      Location:81312
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:9061081
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:285377
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:392475
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13259
      Location:12101326
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17902
      Location:485600
      ArfGap_ARAP3; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 3
      cl17171
      Location:671783
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:11131210
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    RNA

    1. XR_003952486.1 RNA Sequence