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    Syngr2 synaptogyrin 2 [ Mus musculus (house mouse) ]

    Gene ID: 20973, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syngr2provided by MGI
    Official Full Name
    synaptogyrin 2provided by MGI
    Primary source
    MGI:MGI:1328324
    See related
    Ensembl:ENSMUSG00000048277 AllianceGenome:MGI:1328324
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Clast2; cellugyrin
    Summary
    Predicted to be involved in regulated exocytosis and synaptic vesicle membrane organization. Predicted to act upstream of or within protein targeting. Located in synaptic vesicle. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SYNGR2 (synaptogyrin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in colon adult (RPKM 184.2), stomach adult (RPKM 158.3) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Syngr2 in Genome Data Viewer
    Location:
    11 E2; 11 82.96 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (117700459..117705112)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (117809646..117814286)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9147 Neighboring gene predicted gene 11723 Neighboring gene transmembrane channel-like gene family 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:117655547-117655805 Neighboring gene RIKEN cDNA 6030468B19 gene Neighboring gene STARR-positive B cell enhancer ABC_E5305 Neighboring gene STARR-positive B cell enhancer ABC_E5306 Neighboring gene thymidine kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E11501 Neighboring gene STARR-positive B cell enhancer ABC_E4020 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:117693509-117693710 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:117693767-117693876 Neighboring gene arylformamidase Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:117710178-117710379 Neighboring gene baculoviral IAP repeat-containing 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein targeting ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in regulated exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulated exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in synaptic vesicle membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle membrane organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009304.2NP_033330.1  synaptogyrin-2

      See identical proteins and their annotated locations for NP_033330.1

      Status: VALIDATED

      Source sequence(s)
      AK089424, AK150234, BB368123, BY146297
      Consensus CDS
      CCDS25691.1
      UniProtKB/Swiss-Prot
      O55101, Q3TCK2, Q8C225, Q99K83
      UniProtKB/TrEMBL
      B0QZP8
      Related
      ENSMUSP00000026649.8, ENSMUST00000026649.14
      Conserved Domains (1) summary
      pfam01284
      Location:20165
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      117700459..117705112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245751.2XP_030101611.1  synaptogyrin-2 isoform X1

      UniProtKB/TrEMBL
      H3BJ78
      Related
      ENSMUSP00000134879.2, ENSMUST00000175737.2
      Conserved Domains (1) summary
      pfam01284
      Location:20117
      MARVEL; Membrane-associating domain