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    Gpr22 G protein-coupled receptor 22 [ Mus musculus (house mouse) ]

    Gene ID: 73010, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gpr22provided by MGI
    Official Full Name
    G protein-coupled receptor 22provided by MGI
    Primary source
    MGI:MGI:1920260
    See related
    Ensembl:ENSMUSG00000044067 AllianceGenome:MGI:1920260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900068K05Rik
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be active in plasma membrane. Is expressed in adrenal gland; gut; heart; and nervous system. Orthologous to human GPR22 (G protein-coupled receptor 22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 7.8), cortex adult (RPKM 4.9) and 6 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gpr22 in Genome Data Viewer
    Location:
    12 A3; 12 13.69 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (31756866..31763882, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (31706867..31713883, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene B cell receptor associated protein 29 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:32339618-32339801 Neighboring gene dihydrouridine synthase 4 like Neighboring gene STARR-seq mESC enhancer starr_31859 Neighboring gene component of oligomeric golgi complex 5 Neighboring gene STARR-seq mESC enhancer starr_31862 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_31865 Neighboring gene predicted gene, 25913

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (4)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC107197

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptor 22
    Names
    probable G-protein coupled receptor 22

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175191.5NP_780400.3  G-protein coupled receptor 22

      Status: VALIDATED

      Source sequence(s)
      AK034194, AK048077, BC089509
      Consensus CDS
      CCDS25866.3
      UniProtKB/Swiss-Prot
      Q80UE1, Q8BZL4
      UniProtKB/TrEMBL
      G3X9C3
      Related
      ENSMUSP00000056125.6, ENSMUST00000057783.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      31756866..31763882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)