Creb1 cAMP responsive element binding protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Creb1provided by MGI
Official Full Name: cAMP responsive element binding protein 1provided by MGI
Primary source: MGI:MGI:88494
See related: Ensembl:ENSMUSG00000025958 AllianceGenome:MGI:88494
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Creb; Creb-1; 2310001E10Rik; 3526402H21Rik
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in several processes, including cellular response to retinoic acid; protein stabilization; and regulation of lipid biosynthetic process. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; lung development; and nervous system development. Located in chromatin and nucleus. Part of ATF4-CREB1 transcription factor complex. Is expressed in several structures, including brain; genitourinary system; limb; lung; and maxillary process. Human ortholog(s) of this gene implicated in Parkinson's disease; alcohol dependence; and heroin dependence. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 5.1), thymus adult (RPKM 4.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 C2; 1 32.74 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (64571963..64643707)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (64532794..64604548)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Title: Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Intrauterine hyperglycaemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling.
Title: Intrauterine hyperglycaemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling.
Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold.
Title: Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold.
Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis.
Title: Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis.
Enhanced TRPC3 transcription through AT1R/PKA/CREB signaling contributes to mitochondrial dysfunction in renal tubular epithelial cells in D-galactose-induced accelerated aging mice.
Title: Enhanced TRPC3 transcription through AT1R/PKA/CREB signaling contributes to mitochondrial dysfunction in renal tubular epithelial cells in D-galactose-induced accelerated aging mice.
ADENOSINE INFLUENCES FOXP3 EXPRESSION OF T REGS VIA THE A2AR/CREB PATHWAY IN A MOUSE MODEL OF SEPSIS.
Title: ADENOSINE INFLUENCES FOXP3 EXPRESSION OF T REGS VIA THE A2AR/CREB PATHWAY IN A MOUSE MODEL OF SEPSIS.
Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.
Title: Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.
miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in the Early Stages of Alzheimer's Disease: The Anti-Neurodegenerative Effect of Treadmill Exercise.
Title: miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in the Early Stages of Alzheimer's Disease: The Anti-Neurodegenerative Effect of Treadmill Exercise.
Protein kinase D2 confers neuroprotection by promoting AKT and CREB activation in ischemic stroke.
Title: Protein kinase D2 confers neuroprotection by promoting AKT and CREB activation in ischemic stroke.
Neuronal survival factor TAFA2 suppresses apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway.
Title: Neuronal survival factor TAFA2 suppresses apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway.

Submit: New GeneRIF Correction See all GeneRIFs (445)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (5) 1 citation
Targeted (11) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH118240 (e-PCR)
- UniSTS:160915

Creb1 (e-PCR), detects polymorphism
- UniSTS:527295

AV083133 (e-PCR)
- UniSTS:165082

PMC22515P1 (e-PCR)
- UniSTS:272117

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP Inferred from Mutant Phenotype more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISO Inferred from Sequence Orthology more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables Hsp70 protein binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II-specific DNA-binding transcription factor binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II-specific DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables arrestin family protein binding	ISO Inferred from Sequence Orthology more info
enables cAMP response element binding	IBA Inferred from Biological aspect of Ancestor more info
enables cAMP response element binding	IDA Inferred from Direct Assay more info	PubMed
enables cAMP response element binding	ISO Inferred from Sequence Orthology more info
enables double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables enzyme binding	IEA Inferred from Electronic Annotation more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables histone acetyltransferase binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables transcription cis-regulatory region binding	ISO Inferred from Sequence Orthology more info
enables transcription coactivator binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axonogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cAMP/PKA signal transduction	IEA Inferred from Electronic Annotation more info
involved_in cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in cellular response to forskolin	IEA Inferred from Electronic Annotation more info
involved_in cellular response to growth factor stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within cellular response to hepatocyte growth factor stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within cellular response to leukemia inhibitory factor	IEP Inferred from Expression Pattern more info	PubMed
involved_in cellular response to retinoic acid	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cellular response to zinc ion	IDA Inferred from Direct Assay more info	PubMed
involved_in chemotaxis to arachidonate	ISO Inferred from Sequence Orthology more info
involved_in circadian rhythm	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of hormone secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in inhibition of non-skeletal tissue mineralization	ISO Inferred from Sequence Orthology more info	PubMed
acts_upstream_of_or_within lactation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lung epithelium development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lung saccule development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mRNA transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mammary gland development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within memory	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in memory	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by competitive promoter binding	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by competitive promoter binding	ISO Inferred from Sequence Orthology more info
acts_upstream_of osteoclast differentiation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within pituitary gland development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of RNA polymerase II transcription preinitiation complex assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of cardiac muscle tissue development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of fat cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within positive regulation of hormone secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of lipid biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of long-term synaptic potentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of membrane depolarization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of multicellular organism growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of osteoclast differentiation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transforming growth factor beta3 production	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein phosphorylation	ISO Inferred from Sequence Orthology more info	PubMed
involved_in protein stabilization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of cell size	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of fibroblast proliferation	ISO Inferred from Sequence Orthology more info
involved_in regulation of glial cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in regulation of testosterone biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in response to erythropoietin	ISO Inferred from Sequence Orthology more info
involved_in response to ethanol	ISO Inferred from Sequence Orthology more info
involved_in response to glucagon	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to purine-containing compound	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to xenobiotic stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within secretory granule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in transforming growth factor beta receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within type I pneumocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in visual learning	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of ATF4-CREB1 transcription factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ATF4-CREB1 transcription factor complex	IDA Inferred from Direct Assay more info	PubMed
part_of ATF4-CREB1 transcription factor complex	ISO Inferred from Sequence Orthology more info
part_of RNA polymerase II transcription regulator complex	IPI Inferred from Physical Interaction more info	PubMed
part_of RNA polymerase II transcription regulator complex	ISO Inferred from Sequence Orthology more info
located_in axon	ISO Inferred from Sequence Orthology more info
located_in chromatin	IDA Inferred from Direct Assay more info	PubMed
located_in chromatin	IMP Inferred from Mutant Phenotype more info	PubMed
located_in chromatin	ISO Inferred from Sequence Orthology more info
located_in euchromatin	IEA Inferred from Electronic Annotation more info
located_in euchromatin	ISO Inferred from Sequence Orthology more info
located_in mitochondrial matrix	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	TAS Traceable Author Statement more info
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info	PubMed
located_in nucleus	NAS Non-traceable Author Statement more info	PubMed
part_of transcription regulator complex	IDA Inferred from Direct Assay more info	PubMed
part_of transcription regulator complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cyclic AMP-responsive element-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037726.1 → NP_001032815.1 cyclic AMP-responsive element-binding protein 1 isoform C

See identical proteins and their annotated locations for NP_001032815.1

Status: VALIDATED

Description

Transcript Variant: This variant (C) lacks an alternate in-frame exon in the 5' coding region and uses a downstream start codon, compared to variant A. The encoded protein (isoform C) has a shorter N-terminus, compared to isoform A.

Source sequence(s)

AC166336, AK044992, BY315899, CD776417

Consensus CDS

CCDS48280.1

UniProtKB/TrEMBL

Q62347

Related

ENSMUSP00000132860.2, ENSMUST00000171164.8

Conserved Domains (2) summary

cd14690
Location:231 → 285

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:59 → 97

pKID; pKID domain
NM_009952.2 → NP_034082.1 cyclic AMP-responsive element-binding protein 1 isoform B

See identical proteins and their annotated locations for NP_034082.1

Status: VALIDATED

Description

Transcript Variant: This variant (B) includes an alternate in-frame exon in the 5' coding region, compared to variant A, resulting in a longer protein (isoform B), compared to isoform A.

Source sequence(s)

AC124361, BB831364, BY315899, CD776417, M95106

Consensus CDS

CCDS15004.1

UniProtKB/TrEMBL

Q547S9, Q61442

Related

ENSMUSP00000140112.2, ENSMUST00000190348.2

Conserved Domains (2) summary

cd14690
Location:285 → 339

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:113 → 151

pKID; pKID domain
NM_133828.2 → NP_598589.2 cyclic AMP-responsive element-binding protein 1 isoform A

See identical proteins and their annotated locations for NP_598589.2

Status: VALIDATED

Description

Transcript Variant: This variant (A) encodes isoform A.

Source sequence(s)

AC124361, AK044992, BY315899, BY782293, CD776417

Consensus CDS

CCDS15005.1

UniProtKB/Swiss-Prot

Q01147

UniProtKB/TrEMBL

Q543W0, Q61442

Related

ENSMUSP00000084624.5, ENSMUST00000087366.11

Conserved Domains (2) summary

cd14690
Location:271 → 325

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:99 → 137

pKID; pKID domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000067.7 Reference GRCm39 C57BL/6J

Range

64571963..64643707

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006495651.5 → XP_006495714.1 cyclic AMP-responsive element-binding protein 1 isoform X4

See identical proteins and their annotated locations for XP_006495714.1

UniProtKB/Swiss-Prot

Q01147

UniProtKB/TrEMBL

Q543W0, Q61442

Related

ENSMUSP00000139995.2, ENSMUST00000185594.7

Conserved Domains (2) summary

cd14690
Location:271 → 325

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:99 → 137

pKID; pKID domain
XM_006495650.4 → XP_006495713.1 cyclic AMP-responsive element-binding protein 1 isoform X2

See identical proteins and their annotated locations for XP_006495713.1

UniProtKB/TrEMBL

Q547S9, Q61442

Related

ENSMUSP00000059973.6, ENSMUST00000049932.12

Conserved Domains (2) summary

cd14690
Location:285 → 339

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:113 → 151

pKID; pKID domain
XM_006495654.5 → XP_006495717.1 cyclic AMP-responsive element-binding protein 1 isoform X7

UniProtKB/TrEMBL

P70300

Conserved Domains (2) summary

cd14690
Location:210 → 264

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:99 → 137

pKID; pKID domain
XM_006495652.5 → XP_006495715.1 cyclic AMP-responsive element-binding protein 1 isoform X5

See identical proteins and their annotated locations for XP_006495715.1

Conserved Domains (2) summary

cd14690
Location:245 → 299

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:73 → 111

pKID; pKID domain
XM_030245776.2 → XP_030101636.1 cyclic AMP-responsive element-binding protein 1 isoform X10

Conserved Domains (1) summary

cd14690
Location:77 → 131

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
XM_006495653.4 → XP_006495716.1 cyclic AMP-responsive element-binding protein 1 isoform X6

UniProtKB/TrEMBL

P70300

Conserved Domains (2) summary

cd14690
Location:224 → 278

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:113 → 151

pKID; pKID domain
XM_017314080.2 → XP_017169569.1 cyclic AMP-responsive element-binding protein 1 isoform X1

UniProtKB/TrEMBL

Q547S9, Q61442

Conserved Domains (2) summary

cd14690
Location:285 → 339

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:113 → 151

pKID; pKID domain
XM_017314099.2 → XP_017169588.1 cyclic AMP-responsive element-binding protein 1 isoform X3

UniProtKB/Swiss-Prot

Q01147

UniProtKB/TrEMBL

Q543W0, Q61442

Conserved Domains (2) summary

cd14690
Location:271 → 325

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:99 → 137

pKID; pKID domain
XM_036157655.1 → XP_036013548.1 cyclic AMP-responsive element-binding protein 1 isoform X8

UniProtKB/TrEMBL

P70300

Conserved Domains (2) summary

cd14690
Location:210 → 264

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:99 → 137

pKID; pKID domain
XM_036157665.1 → XP_036013558.1 cyclic AMP-responsive element-binding protein 1 isoform X9

UniProtKB/TrEMBL

P70300

Conserved Domains (2) summary

cd14690
Location:170 → 224

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

pfam02173
Location:59 → 97

pKID; pKID domain
XM_011238424.3 → XP_011236726.1 cyclic AMP-responsive element-binding protein 1 isoform X10

See identical proteins and their annotated locations for XP_011236726.1

Conserved Domains (1) summary

cd14690
Location:77 → 131

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
XM_011238425.2 → XP_011236727.1 cyclic AMP-responsive element-binding protein 1 isoform X10

See identical proteins and their annotated locations for XP_011236727.1

Conserved Domains (1) summary

cd14690
Location:77 → 131

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
XM_006495655.5 → XP_006495718.1 cyclic AMP-responsive element-binding protein 1 isoform X11

Conserved Domains (1) summary

cd14690
Location:55 → 109

bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain