U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nipal4 NIPA-like domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 214112, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nipal4provided by MGI
    Official Full Name
    NIPA-like domain containing 4provided by MGI
    Primary source
    MGI:MGI:2444671
    See related
    Ensembl:ENSMUSG00000020411 AllianceGenome:MGI:2444671
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9530066K23Rik
    Summary
    Predicted to enable magnesium ion transmembrane transporter activity. Involved in magnesium ion transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 6. Orthologous to human NIPAL4 (NIPA like domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in bladder adult (RPKM 18.3), stomach adult (RPKM 7.1) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nipal4 in Genome Data Viewer
    Location:
    11 B1.1; 11 27.59 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (46038982..46057186, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (46148155..46166359, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10671 Neighboring gene SFT2 domain containing 1, retrotransposed Neighboring gene ADAM metallopeptidase domain 19 Neighboring gene STARR-seq mESC enhancer starr_29320 Neighboring gene STARR-seq mESC enhancer starr_29321 Neighboring gene microRNA 8100 Neighboring gene STARR-positive B cell enhancer ABC_E3942 Neighboring gene STARR-positive B cell enhancer ABC_E8393 Neighboring gene STARR-positive B cell enhancer ABC_E5219 Neighboring gene predicted gene, 35624 Neighboring gene microRNA 7239 Neighboring gene VISTA enhancer mm102 Neighboring gene cytoplasmic FMR1 interacting protein 2 Neighboring gene fibronectin type III domain containing 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables magnesium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in magnesium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in magnesium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in magnesium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    magnesium transporter NIPA4
    Names
    NIPA-like protein 4
    ichthyin
    non-imprinted in Prader-Willi/Angelman syndrome region protein 4 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172524.3NP_766112.1  magnesium transporter NIPA4

      See identical proteins and their annotated locations for NP_766112.1

      Status: VALIDATED

      Source sequence(s)
      AL663031, AL713958
      Consensus CDS
      CCDS24572.1
      UniProtKB/Swiss-Prot
      A4QPF8, Q8BZF2
      Related
      ENSMUSP00000020679.3, ENSMUST00000020679.3
      Conserved Domains (1) summary
      cl23754
      Location:56350
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      46038982..46057186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)