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    Timd6 T cell immunoglobulin and mucin domain containing 6 [ Mus musculus (house mouse) ]

    Gene ID: 407814, updated on 9-Dec-2024

    Summary

    Official Symbol
    Timd6provided by MGI
    Official Full Name
    T cell immunoglobulin and mucin domain containing 6provided by MGI
    Primary source
    MGI:MGI:3039605
    See related
    Ensembl:ENSMUSG00000046974 AllianceGenome:MGI:3039605
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable phosphatidylserine binding activity and virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to be located in motile cilium. Predicted to be active in cell surface. Is expressed in eye; ovary; and testis. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Timd6 in Genome Data Viewer
    Location:
    11 B1.1; 11 28.0 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (46462340..46480059)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (46571513..46589232)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 1 family member pseudogene Neighboring gene STARR-seq mESC enhancer starr_29332 Neighboring gene ribosomal protein L9, pseudogene 2 Neighboring gene developmental pluripotency associated 1 Neighboring gene T cell immunoglobulin and mucin domain containing 7, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatidylserine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables virus receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables virus receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in phagocytosis, engulfment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of mast cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in motile cilium ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC407814
    Names
    hepatitis A virus cellular receptor 1-like family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025435.3NP_001020606.2  uncharacterized protein LOC407814 precursor

      See identical proteins and their annotated locations for NP_001020606.2

      Status: PREDICTED

      Source sequence(s)
      AL669948
      Consensus CDS
      CCDS24580.1
      UniProtKB/TrEMBL
      A0A0B4J1F6, Q7TQ03
      Related
      ENSMUSP00000050057.7, ENSMUST00000050937.7
      Conserved Domains (2) summary
      smart00410
      Location:23111
      IG_like; Immunoglobulin like
      pfam07686
      Location:30110
      V-set; Immunoglobulin V-set domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      46462340..46480059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)