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    TotF Turandot F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117461, updated on 4-Jan-2025

    Summary

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    Official Symbol
    TotFprovided by FlyBase
    Official Full Name
    Turandot Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0044811
    Locus tag
    Dmel_CG31691
    See related
    AllianceGenome:FB:FBgn0044811
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13963; CG31691; Dmel\CG31691; tot; Tot F
    Summary
    Involved in several processes, including cellular response to UV; cellular response to heat; and response to virus. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See TotF in Genome Data Viewer
    Location:
    38A7-38A7; 2-54 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19911815..19912377, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19911815..19912377, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene sickie Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43097 Neighboring gene long non-coding RNA:CR43828 Neighboring gene Turandot E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Insulin-mediated endothelin signaling is antiviral during West Nile virus infection. Trammell CE, et al. J Virol, 2023 Oct 31. PMID 37796127, Free PMC Article
    2. Exploring cross-protective effects between cold and immune stress in Drosophila melanogaster. Wiil J, et al. Parasite, 2023. PMID 38084935, Free PMC Article
    3. Anti-Tumor Effect of Turandot Proteins Induced via the JAK/STAT Pathway in the mxc Hematopoietic Tumor Mutant in Drosophila. Kinoshita Y, et al. Cells, 2023 Aug 11. PMID 37626857, Free PMC Article
    4. A family of Turandot-related genes in the humoral stress response of Drosophila. Ekengren S, et al. Biochem Biophys Res Commun, 2001 Jun 22. PMID 11409894
    5. The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway. Abe T, et al. Development, 2014 Dec. PMID 25411210

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to UV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to virus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    turandot F
    Names
    CG31691-PA
    TotF-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19911815..19912377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080519.4 → NP_536780.3  turandot F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_536780.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q962D8, Q9VIR2
      UniProtKB/TrEMBL
      D4G7E3
      Conserved Domains (1) summary
      pfam07240
      Location:43 → 122
      Turandot; Stress-inducible humoral factor Turandot
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIR2.3 Q9VIR2

    Gene LinkOut

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