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    CG5116 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43081, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5116provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039339
    Locus tag
    Dmel_CG5116
    See related
    AllianceGenome:FB:FBgn0039339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5116; Dromel_CG5116_FBtr0084877_mORF
    Summary
    Predicted to enable ribosome binding activity. Predicted to be active in cytoplasm. Is expressed in spermatozoon. Orthologous to human GTPBP6 (GTP binding protein 6 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5116 in Genome Data Viewer
    Location:
    96E2-96E2; 3-88 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25483098..25485855)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21308820..21311577)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mediator complex subunit 28 Neighboring gene XNP Neighboring gene uncharacterized protein Neighboring gene Glyceronephosphate O-acyltransferase Neighboring gene antisense RNA:CR44179 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The chromatin remodelling factor dATRX is involved in heterochromatin formation. Bassett AR, et al. PLoS One, 2008 May 7. PMID 18461125, Free PMC Article
    2. Parallel and population-specific gene regulatory evolution in cold-adapted fly populations. Huang Y, et al. Genetics, 2021 Jul 14. PMID 33989401, Free PMC Article
    3. Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes. Takahashi H, et al. Sci Rep, 2020 Oct 1. PMID 33004976, Free PMC Article
    4. Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. Hayden CA, et al. BMC Genomics, 2008 Feb 1. PMID 18237443, Free PMC Article
    5. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5116-PA
    CG5116-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25483098..25485855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300600.1 → NP_001287529.1  uncharacterized protein Dmel_CG5116, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287529.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYD1, Q9VBQ7
      Conserved Domains (4) summary
      cd01878
      Location:259 → 464
      HflX; HflX GTPase family
      COG2262
      Location:122 → 525
      HflX; 50S ribosomal subunit-associated GTPase HflX [Translation, ribosomal structure and biogenesis]
      pfam13167
      Location:124 → 216
      GTP-bdg_N; GTP-binding GTPase N-terminal
      pfam16360
      Location:220 → 279
      GTP-bdg_M; GTP-binding GTPase Middle Region

    2. NM_143142.4 → NP_651399.2  uncharacterized protein Dmel_CG5116, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651399.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYD1, Q9VBQ7
      Related
      FBpp0084251
      Conserved Domains (4) summary
      cd01878
      Location:259 → 464
      HflX; HflX GTPase family
      COG2262
      Location:122 → 525
      HflX; 50S ribosomal subunit-associated GTPase HflX [Translation, ribosomal structure and biogenesis]
      pfam13167
      Location:124 → 216
      GTP-bdg_N; GTP-binding GTPase N-terminal
      pfam16360
      Location:220 → 279
      GTP-bdg_M; GTP-binding GTPase Middle Region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYD1 Q8SYD1
    Q9VBQ7 Q9VBQ7

    Gene LinkOut

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