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    lectin-24Db lectin-24Db [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 53550, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lectin-24Dbprovided by FlyBase
    Official Full Name
    lectin-24Dbprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040102
    Locus tag
    Dmel_CG2958
    See related
    AllianceGenome:FB:FBgn0040102
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC 004371A; AC004371a; CG2958; Dmel\CG2958; Lectin 24Db
    Summary
    Enables D-mannose binding activity; fucose binding activity; and glycosylated region protein binding activity. Predicted to be involved in immune response. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lectin-24Db in Genome Data Viewer
    Location:
    24D8-24D8; 2-11 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4188123..4189284)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4188123..4189284)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45791 Neighboring gene long non-coding RNA:CR44057 Neighboring gene Tubulin-binding cofactor C Neighboring gene Nicotinate phosphoribosyltransferase Neighboring gene fat

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues. Bouyain S, et al. J Biol Chem, 2002 Jun 21. PMID 11960993
    2. A rapid genome-wide response to Drosophila melanogaster social interactions. Carney GE. BMC Genomics, 2007 Aug 22. PMID 17714588, Free PMC Article
    3. Glycosylation of proteins in plants and invertebrates. Wilson IB. Curr Opin Struct Biol, 2002 Oct. PMID 12464307
    4. The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors. Green L, et al. BMC Biol, 2022 Dec 8. PMID 36482348, Free PMC Article
    5. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a potential endogenous receptor for neural-specific carbohydrate epitopes
      Title: An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-mannose binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fucose binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycosylated region protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lectin-24Db
    Names
    CG2958-PA
    Lectin24DB
    lectin
    lectin-24Db-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4188123..4189284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144384.3 → NP_652641.1  lectin-24Db [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652641.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQX3
      Related
      FBpp0077158
      Conserved Domains (3) summary
      cd00037
      Location:247 → 354
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      pfam16806
      Location:44 → 156
      ExsD; Antiactivator protein ExsD
      cl17182
      Location:170 → 229
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQX3 Q9VQX3

    Gene LinkOut

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