EloA Elongin A [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: EloAprovided by FlyBase
Official Full Name: Elongin Aprovided by FlyBase
Primary source: FLYBASE:FBgn0039066
Locus tag: Dmel_CG6755
See related: AllianceGenome:FB:FBgn0039066
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6755; dEloA; Dmel\CG6755; Elo-A
Summary: Involved in imaginal disc-derived wing vein specification and transcription elongation by RNA polymerase II. Located in nucleus. Part of elongin complex. Colocalizes with euchromatin. Is expressed in several structures, including adult head; anlage in statu nascendi; antennal anlage; central brain anlage; and central brain anlage in statu nascendi. Used to study candidiasis. Orthologous to several human genes including ELOA2 (elongin A2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (23251563..23255071)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (19077285..19080793)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in imaginal disc-derived wing vein specification	IGI Inferred from Genetic Interaction more info	PubMed
involved_in imaginal disc-derived wing vein specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription elongation by RNA polymerase II	IC Inferred by Curator more info	PubMed
involved_in transcription elongation by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in transcription elongation by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of elongin complex	IDA Inferred from Direct Assay more info	PubMed
part_of elongin complex	IEA Inferred from Electronic Annotation more info
part_of elongin complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
colocalizes_with euchromatin	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription elongation factor complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain