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    CG5250 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42308, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5250provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038691
    Locus tag
    Dmel_CG5250
    See related
    AllianceGenome:FB:FBgn0038691
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5250
    Summary
    Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be part of sodium:potassium-exchanging ATPase complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5250 in Genome Data Viewer
    Location:
    91F12-91F12; 3-66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19228217..19229276, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15053939..15054998, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene cryptochrome Neighboring gene vibrator Neighboring gene uncharacterized protein Neighboring gene RNA polymerase II subunit M Neighboring gene uncoordinated 79 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. P-type ATPases in Caenorhabditis and Drosophila: implications for evolution of the P-type ATPase subunit families with special reference to the Na,K-ATPase and H,K-ATPase subgroup. Okamura H, et al. J Membr Biol, 2003 Jan 1. PMID 12532273
    2. Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Stevaux O, et al. Cell Cycle, 2005 Sep. PMID 16082225
    3. Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster. Szlanka T, et al. G3 (Bethesda), 2024 Sep 4. PMID 38985658, Free PMC Article
    4. A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity. Longworth MS, et al. PLoS Genet, 2012. PMID 22496667, Free PMC Article
    5. RBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexes. Korenjak M, et al. Mol Cell Biol, 2012 Nov. PMID 22927638, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular sodium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion export across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of sodium:potassium-exchanging ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of sodium:potassium-exchanging ATPase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5250-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19228217..19229276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142536.2 → NP_650793.1  uncharacterized protein Dmel_CG5250 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650793.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDY7
      Related
      FBpp0083157
      Conserved Domains (1) summary
      cl08255
      Location:143 → 281
      Na_K-ATPase; Sodium / potassium ATPase beta chain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDY7 Q9VDY7

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