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    CG10232 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42800, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10232provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039108
    Locus tag
    Dmel_CG10232
    See related
    AllianceGenome:FB:FBgn0039108
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cSP14; Dmel\CG10232; SP14
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10232 in Genome Data Viewer
    Location:
    95B1-95B1; 3-80 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23719343..23721625, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19545065..19547347, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene nautilus Neighboring gene uncharacterized protein Neighboring gene Ribonuclease MRP RNA Neighboring gene Regulatory particle non-ATPase 9 Neighboring gene HMG Coenzyme A reductase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intermolecular Interactions Drive Protein Adaptive and Coadaptive Evolution at Both Species and Population Levels. Peng J, et al. Mol Biol Evol, 2022 Jan 7. PMID 34878126, Free PMC Article
    2. Gene Protein Sequence Evolution Can Predict the Rapid Divergence of Ovariole Numbers in the Drosophila melanogaster Subgroup. Whittle CA, et al. Genome Biol Evol, 2024 Jul 3. PMID 38848313, Free PMC Article
    3. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
    4. dusky-like is required to maintain the integrity and planar cell polarity of hairs during the development of the Drosophila wing. Adler PN, et al. Dev Biol, 2013 Jul 1. PMID 23623898, Free PMC Article
    5. The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity. Kwon SY, et al. Dev Biol, 2008 Apr 15. PMID 18334252

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10232-PD
    NP_651175.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23719343..23721625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142918.4 → NP_651175.4  uncharacterized protein Dmel_CG10232 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651175.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCJ0
      Conserved Domains (2) summary
      smart00020
      Location:260 → 503
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:260 → 506
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VCJ0 Q9VCJ0

    Gene LinkOut

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