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    CG4452 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39069, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG4452provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035981
    Locus tag
    Dmel_CG4452
    See related
    AllianceGenome:FB:FBgn0035981
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.118; cg4452; Dmel\CG4452
    Summary
    Predicted to be active in nuclear speck. Is expressed in several structures, including antennal primordium; cardiogenic mesoderm; ganglia; head epidermis primordium; and somatic trunk mesoderm derivative. Orthologous to human FAM76A (family with sequence similarity 76 member A) and FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4452 in Genome Data Viewer
    Location:
    67B2-67B2; 3-29 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9367377..9370300)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9360477..9363400)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Kinesin-like protein at 67A Neighboring gene mitochondrial ribosome recycling factor 1 Neighboring gene Ferredoxin 1 Neighboring gene Heat shock gene 67Bc Neighboring gene uncharacterized protein Neighboring gene Heat shock protein 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coincidence of P-insertion sites and breakpoints of deletions induced by activating P elements in Drosophila. Sudi J, et al. Genetics, 2008 May. PMID 18493052, Free PMC Article
    2. Timing and targeting of P-element local transposition in the male germline cells of Drosophila melanogaster. Timakov B, et al. Genetics, 2002 Mar. PMID 11901118, Free PMC Article
    3. Genome-wide analysis of nuclear mRNA export pathways in Drosophila. Herold A, et al. EMBO J, 2003 May 15. PMID 12743041, Free PMC Article
    4. Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster. Parker GA, et al. G3 (Bethesda), 2020 Mar 5. PMID 31969430, Free PMC Article
    5. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4452-PA
    CG4452-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9367377..9370300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274696.1 → NP_001261625.1  uncharacterized protein Dmel_CG4452, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261625.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEW8
      Conserved Domains (1) summary
      pfam16046
      Location:6 → 89
      FAM76; FAM76 protein

    2. NM_140046.4 → NP_648303.1  uncharacterized protein Dmel_CG4452, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSW7
      Related
      FBpp0088493
      Conserved Domains (1) summary
      pfam16046
      Location:6 → 310
      FAM76; FAM76 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEW8 M9PEW8
    Q8IH34 Q8IH34
    Q9VSW7 Q9VSW7

    Gene LinkOut

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