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    CG4866 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36976, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4866provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034232
    Locus tag
    Dmel_CG4866
    See related
    AllianceGenome:FB:FBgn0034232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4866; mRpS4
    Summary
    Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be part of Mpp10 complex and small-subunit processome. Is expressed in organism. Orthologous to human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4866 in Genome Data Viewer
    Location:
    54C1-54C1; 2-83 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17518223..17519027)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13405728..13406532)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cathepsin K2 Neighboring gene uncharacterized protein Neighboring gene Anaphase Promoting Complex subunit 10 Neighboring gene patronin Neighboring gene eukaryotic translation initiation factor 3 subunit b Neighboring gene Coiled-coil and C2 domain containing 2A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    2. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
    3. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Comparative interactome analysis of α-arrestin families in human and Drosophila. Lee KT, et al. Elife, 2024 Jan 25. PMID 38270169, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Mpp10 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4866-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17518223..17519027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137380.3 → NP_611224.1  uncharacterized protein Dmel_CG4866 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611224.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JZ53
      Related
      FBpp0086096
      Conserved Domains (2) summary
      COG0522
      Location:1 → 166
      RpsD; Ribosomal protein S4 or related protein [Translation, ribosomal structure and biogenesis]
      pfam01479
      Location:108 → 154
      S4; S4 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JZ53 Q7JZ53

    Gene LinkOut

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