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    jigr1 jing interacting gene regulatory 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43093, updated on 9-Dec-2024

    Summary

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    Official Symbol
    jigr1provided by FlyBase
    Official Full Name
    jing interacting gene regulatory 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0039350
    Locus tag
    Dmel_CG17383
    See related
    AllianceGenome:FB:FBgn0039350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs29f05.y1; CG17383; Dmel\CG17383; JIGR-1; JIGR1; son
    Summary
    Predicted to enable transcription cis-regulatory region binding activity. Involved in neuroblast differentiation. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including antennal anlage; cuboidal/columnar epithelium; ganglia; head epidermis primordium; and imaginal disc. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See jigr1 in Genome Data Viewer
    Location:
    96E6-96E6; 3-88 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25637843..25651874)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21463565..21476119)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Nuclear protein localization 4 Neighboring gene uncharacterized protein Neighboring gene Succinic semialdehyde dehydrogenase Neighboring gene long non-coding RNA:CR45917 Neighboring gene mir-92a stem loop Neighboring gene mir-92b stem loop Neighboring gene antisense RNA:CR46101 Neighboring gene tankyrase Neighboring gene antisense RNA:CR45208 Neighboring gene Ras association domain family member 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development. Chen Z, et al. Development, 2012 Oct. PMID 22899845, Free PMC Article
    2. Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila. Yuva-Aydemir Y, et al. PLoS Genet, 2015 May. PMID 26000445, Free PMC Article
    3. Son of Notch, a winged-helix gene involved in boundary formation in the Drosophila wing. Park E, et al. IUBMB Life, 2007 Dec. PMID 18085478, Free PMC Article
    4. A role for the serine/arginine-rich (SR) protein B52/SRSF6 in cell growth and myc expression in Drosophila. Fernando C, et al. Genetics, 2015 Apr. PMID 25680814, Free PMC Article
    5. Glial and neuronal functions of the Drosophila homolog of the human SWI/SNF gene ATR-X (DATR-X) and the jing zinc-finger gene specify the lateral positioning of longitudinal glia and axons. Sun X, et al. Genetics, 2006 Jul. PMID 16648585, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription cis-regulatory region binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuroblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of gene expression ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    jing interacting gene regulatory 1
    Names
    CG17383-PA
    CG17383-PB
    CG17383-PC
    CG17383-PD
    CG17383-PE
    CG17383-PF
    CG17383-PG
    CG17383-PH
    jigr1-PA
    jigr1-PB
    jigr1-PC
    jigr1-PD
    jigr1-PE
    jigr1-PF
    jigr1-PG
    jigr1-PH
    son of notch

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25637843..25651874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001347754.1 → NP_001334702.1  jing interacting gene regulatory 1, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5

    2. NM_001104450.2 → NP_001097920.1  jing interacting gene regulatory 1, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097920.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    3. NM_143152.4 → NP_651409.1  jing interacting gene regulatory 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651409.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Related
      FBpp0084261
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    4. NM_170233.2 → NP_733112.1  jing interacting gene regulatory 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Related
      FBpp0084260
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    5. NM_170235.3 → NP_733114.1  jing interacting gene regulatory 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733114.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Related
      FBpp0084262
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    6. NM_170234.1 → NP_733113.1  jing interacting gene regulatory 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733113.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Related
      FBpp0084263, FBtr0084889
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    7. NM_001104451.2 → NP_001097921.1  jing interacting gene regulatory 1, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097921.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain

    8. NM_001276033.1 → NP_001262962.1  jing interacting gene regulatory 1, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262962.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBP5
      Conserved Domains (1) summary
      smart00595
      Location:33 → 118
      MADF; subfamily of SANT domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBP5 Q9VBP5

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