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    RpL34a Ribosomal protein L34a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43169, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL34aprovided by FlyBase
    Official Full Name
    Ribosomal protein L34aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039406
    Locus tag
    Dmel_CG6090
    See related
    AllianceGenome:FB:FBgn0039406
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6090; Dmel\CG6090; L34; L34e; RpL34
    Summary
    Enables myosin binding activity. A structural constituent of ribosome. Predicted to be involved in ribosome biogenesis and translation. Located in cytosolic ribosome. Is expressed in adult head and organism. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL34a in Genome Data Viewer
    Location:
    96F10-96F10; 3-89 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26058420..26059267, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21884142..21884989, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sld5 Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class P Neighboring gene Threonyl-carbamoyl synthesis 6 Neighboring gene tRNA methyltransferase 61 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44950

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deletion of Drosophila Nopp140 induces subcellular ribosomopathies. He F, et al. Chromosoma, 2015 Jun. PMID 25384888
    2. Loss of Drosophila nucleostemin 2 (NS2) blocks nucleolar release of the 60S subunit leading to ribosome stress. Wang Y, et al. Chromosoma, 2017 Jun. PMID 27150106
    3. Relating past and present diet to phenotypic and transcriptomic variation in the fruit fly. May CM, et al. BMC Genomics, 2017 Aug 22. PMID 28830340, Free PMC Article
    4. Cdk12 Is A Gene-Selective RNA Polymerase II Kinase That Regulates a Subset of the Transcriptome, Including Nrf2 Target Genes. Li X, et al. Sci Rep, 2016 Feb 25. PMID 26911346, Free PMC Article
    5. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables myosin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation ISM
    Inferred from Sequence Model
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L34a
    Names
    CG6090-PA
    CG6090-PB
    CG6090-PC
    RpL34a-PA
    RpL34a-PB
    RpL34a-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26058420..26059267 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202366.1 → NP_001189295.1  ribosomal protein L34a, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189295.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYG0, Q9VBH8
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 94
      Ribosomal_L34e; Ribosomal protein L34e

    2. NM_143203.3 → NP_651460.2  ribosomal protein L34a, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651460.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYG0, Q9VBH8
      Related
      FBpp0084345
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 94
      Ribosomal_L34e; Ribosomal protein L34e

    3. NM_170257.3 → NP_733136.1  ribosomal protein L34a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733136.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYG0, Q9VBH8
      Related
      FBpp0084346
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 94
      Ribosomal_L34e; Ribosomal protein L34e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYG0 Q8SYG0
    Q9VBH8 Q9VBH8

    Gene LinkOut

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