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    CG11911 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33206, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG11911provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031249
    Locus tag
    Dmel_CG11911
    See related
    AllianceGenome:FB:FBgn0031249
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11911; SP103
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11911 in Genome Data Viewer
    Location:
    21B8-21B8; 2-0.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (320279..321248, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (320279..321248, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43719 Neighboring gene Phospholipase C at 21C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster. Lundberg LE, et al. Nucleic Acids Res, 2012 Jul. PMID 22434883, Free PMC Article
    2. The Drosophila early ovarian transcriptome provides insight to the molecular causes of recombination rate variation across genomes. Adrian AB, et al. BMC Genomics, 2013 Nov 15. PMID 24228734, Free PMC Article
    3. Immune-inducible non-coding RNA molecule lincRNA-IBIN connects immunity and metabolism in Drosophila melanogaster. Valanne S, et al. PLoS Pathog, 2019 Jan. PMID 30633769, Free PMC Article
    4. Unanchored ubiquitin chains do not lead to marked alterations in gene expression in Drosophila melanogaster. Blount JR, et al. Biol Open, 2019 May 30. PMID 31097444, Free PMC Article
    5. Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging. Jiao J, et al. Cell Rep, 2023 Jan 31. PMID 36640359, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11911-PA
    NP_608518.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      320279..321248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134674.2 → NP_608518.1  uncharacterized protein Dmel_CG11911 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQQ2, Q9VPN8
      Related
      FBpp0077757
      Conserved Domains (2) summary
      smart00020
      Location:37 → 266
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:37 → 269
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQQ2 Q8MQQ2
    Q9VPN8 Q9VPN8

    Gene LinkOut

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