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    CG15141 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35044, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15141provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032635
    Locus tag
    Dmel_CG15141
    See related
    AllianceGenome:FB:FBgn0032635
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD24839; Dmel\CG15141; UBR7
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is expressed in several structures, including central brain primordium; embryonic brain; embryonic central brain neurons; somatic precursor cell; and ventral nerve cord. Orthologous to human UBR7 (ubiquitin protein ligase E3 component n-recognin 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15141 in Genome Data Viewer
    Location:
    36C7-36C7; 2-53 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17410641..17413499)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17410641..17413499)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cytoplasmic linker protein 190 Neighboring gene RNA polymerase II subunit J Neighboring gene Radial spoke head protein 9 Neighboring gene Dorsal-related immunity factor Neighboring gene long non-coding RNA:CR44409 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inactivation of effector caspases through nondegradative polyubiquitylation. Ditzel M, et al. Mol Cell, 2008 Nov 21. PMID 19026784, Free PMC Article
    2. The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2016 Aug. PMID 27552662, Free PMC Article
    3. Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. Herr DR, et al. FEBS Lett, 2004 Aug 13. PMID 15304339
    4. The PHD finger, a nuclear protein-interaction domain. Bienz M. Trends Biochem Sci, 2006 Jan. PMID 16297627
    5. Expression profiling of glial genes during Drosophila embryogenesis. Altenhein B, et al. Dev Biol, 2006 Aug 15. PMID 16762338

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15141-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      17410641..17413499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135993.4 → NP_609837.1  uncharacterized protein Dmel_CG15141 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609837.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJE3
      Related
      FBpp0080532
      Conserved Domains (2) summary
      cd15542
      Location:145 → 199
      PHD_UBR7; PHD finger found in putative E3 ubiquitin-protein ligase UBR7
      pfam02207
      Location:62 → 122
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJE3 Q9VJE3

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