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    CG12620 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35034, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12620provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032626
    Locus tag
    Dmel_CG12620
    See related
    AllianceGenome:FB:FBgn0032626
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12620
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Orthologous to several human genes including PPP1R2B (PPP1R2 family member B); PPP1R2C (PPP1R2C family member C); and PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12620 in Genome Data Viewer
    Location:
    36B8-36B8; 2-53 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17087641..17089186)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17087641..17089186)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43819 Neighboring gene long non-coding RNA:CR45448 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    3. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12620-PA
    CG12620-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      17087641..17089186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273596.1 → NP_001260525.1  uncharacterized protein Dmel_CG12620, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260525.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V424, Q9VJF4
      Conserved Domains (1) summary
      pfam04979
      Location:21 → 111
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)

    2. NM_135984.2 → NP_609828.2  uncharacterized protein Dmel_CG12620, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609828.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V424, Q9VJF4
      Conserved Domains (1) summary
      pfam04979
      Location:21 → 111
      IPP-2; Protein phosphatase inhibitor 2 (IPP-2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V424 Q4V424

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