Smug Single-strand-selective monofunctional uracil-DNA glycosylase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Smugprovided by FlyBase
Official Full Name: Single-strand-selective monofunctional uracil-DNA glycosylaseprovided by FlyBase
Primary source: FLYBASE:FBgn0038490
Locus tag: Dmel_CG5285
See related: AllianceGenome:FB:FBgn0038490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5285; CG5285_Dm_7300236; Dmel\CG5285; dmSMUG1; SMUG; SMUG1; ssUDG
Summary: Predicted to enable oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity and uracil DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Orthologous to human SMUG1 (single-strand-selective monofunctional uracil-DNA glycosylase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (17150587..17151630)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (12976309..12977352)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables single-strand selective uracil DNA N-glycosylase activity	IEA Inferred from Electronic Annotation more info
enables uracil DNA N-glycosylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables uracil DNA N-glycosylase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in base-excision repair	IEA Inferred from Electronic Annotation more info
involved_in base-excision repair	ISS Inferred from Sequence or Structural Similarity more info

Preferred Names: Single-strand-selective monofunctional uracil-DNA glycosylase

Names: CG5285-PA; Smug-PA; single-strand-specific UDG; single-strand-specific monofunctional uracil-DNA glycosylase 1; uracil-DNA glycosylase

NP_650609.1

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The following sections contain reference sequences that belong to a specific genome build. Explain