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    CG5958 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34022, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5958provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031913
    Locus tag
    Dmel_CG5958
    See related
    AllianceGenome:FB:FBgn0031913
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5958
    Summary
    Predicted to enable phosphatidylinositol bisphosphate binding activity and retinal binding activity. Predicted to be involved in response to light stimulus. Located in cytoplasm. Is expressed in several structures, including adult head; adult heart; amnioserosa; embryonic/larval hemocyte; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to several human genes including TTPAL (alpha tocopherol transfer protein like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5958 in Genome Data Viewer
    Location:
    27F4-27F4; 2-26 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7430530..7433516, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7430530..7433516, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene mir-305 stem loop Neighboring gene midline uncoordinated Neighboring gene uncharacterized protein Neighboring gene scavenger receptor acting in neural tissue and majority of rhodopsin is absent Neighboring gene Gustatory receptor 28a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction. Wang T, et al. J Cell Biol, 2007 Apr 23. PMID 17452532, Free PMC Article
    2. Genome-wide transcriptional orchestration of circadian rhythms in Drosophila. Ueda HR, et al. J Biol Chem, 2002 Apr 19. PMID 11854264
    3. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
    4. Characterization of the Drosophila lipid droplet subproteome. Beller M, et al. Mol Cell Proteomics, 2006 Jun. PMID 16543254
    5. Gene expression during the life cycle of Drosophila melanogaster. Arbeitman MN, et al. Science, 2002 Sep 27. PMID 12351791

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables retinal binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to light stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5958-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7430530..7433516 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135275.3 → NP_609119.2  uncharacterized protein Dmel_CG5958 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609119.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYZ8, Q9VM12
      Related
      FBpp0079090
      Conserved Domains (2) summary
      smart01100
      Location:38 → 82
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:111 → 261
      CRAL_TRIO; CRAL/TRIO domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYZ8 Q8SYZ8
    Q9VM12 Q9VM12

    Gene LinkOut

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