U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ppan peter pan [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42502, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ppanprovided by FlyBase
    Official Full Name
    peter panprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010770
    Locus tag
    Dmel_CG5786
    See related
    AllianceGenome:FB:FBgn0010770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5786; Dmel\CG5786; l(3)02231; l(3)j6B6; Ppan; PPAN; SSF1
    Summary
    Predicted to enable rRNA binding activity. Involved in female gamete generation; imaginal disc development; and larval development. Predicted to be part of preribosome, large subunit precursor. Is expressed in organism. Orthologous to human PPAN-P2RY11 (PPAN-P2RY11 readthrough) and PPAN (peter pan homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ppan in Genome Data Viewer
    Location:
    93B13-93B13; 3-70 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21116254..21117899)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16941976..16943621)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene tetracycline resistance Neighboring gene Rab11 Neighboring gene Bride of doubletime Neighboring gene supernumerary limbs Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 93a

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth. Migeon JC, et al. Mol Biol Cell, 1999 Jun. PMID 10359593, Free PMC Article
    2. The archaeal homolog of the Imp4 protein, a eukaryotic U3 snoRNP component. Mayer C, et al. Trends Biochem Sci, 2001 Mar. PMID 11246005
    3. An RNAi screen for ribosome biogenesis genes required for Drosophila border cell collective migration. Burghardt E, et al. MicroPubl Biol, 2024. PMID 39185014, Free PMC Article
    4. The EGF/Ras pathway controls growth in Drosophila via ribosomal RNA synthesis. Sriskanthadevan-Pirahas S, et al. Dev Biol, 2018 Jul 1. PMID 29660312
    5. Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation. Zielke N, et al. Dev Cell, 2022 Apr 25. PMID 35472319

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in female gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in imaginal disc development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in larval development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    peter pan
    Names
    CG5786-PA
    peterpan
    ppan-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21116254..21117899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057631.6 → NP_476979.1  peter pan [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476979.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97133, Q9VDE5
      Related
      FBpp0083415
      Conserved Domains (2) summary
      smart00879
      Location:31 → 212
      Brix; The Brix domain is found in a number of eukaryotic proteins
      cl00935
      Location:215 → 295
      Brix; Brix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BIK3 Q5BIK3
    Q9VDE5.1 Q9VDE5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools