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    beat-IIIc beaten path IIIc [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35037, updated on 9-Dec-2024

    Summary

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    Official Symbol
    beat-IIIcprovided by FlyBase
    Official Full Name
    beaten path IIIcprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032629
    Locus tag
    Dmel_CG15138
    See related
    AllianceGenome:FB:FBgn0032629
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE14414; beat IIIc; Beat-IIIc; Beat-IIIC; CG15138; CG6365; Dmel\CG15138
    Summary
    Involved in motor neuron axon guidance and synaptic target inhibition. Is expressed in several structures, including apoptotic amnioserosa; embryonic/larval midgut primordium; ganglia; mesoderm; and visceral mesoderm derivative. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See beat-IIIc in Genome Data Viewer
    Location:
    36C2-36C4; 2-53 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17187637..17260734, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17187637..17260734, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 36c Neighboring gene Gustatory receptor-like 36a Neighboring gene long non-coding RNA:CR44396 Neighboring gene long non-coding RNA:CR44395 Neighboring gene long non-coding RNA:CR45729 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Combining genome-wide methods to investigate the genetic complexity of courtship song variation in Drosophila melanogaster. Turner TL, et al. Mol Biol Evol, 2013 Sep. PMID 23777628, Free PMC Article
    2. Wnt4 is a local repulsive cue that determines synaptic target specificity. Inaki M, et al. Curr Biol, 2007 Sep 18. PMID 17764943
    3. Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity. Osaka J, et al. Cell Rep, 2024 Feb 27. PMID 38381608
    4. The Beat generation: a multigene family encoding IgSF proteins related to the Beat axon guidance molecule in Drosophila. Pipes GC, et al. Development, 2001 Nov. PMID 11714679
    5. Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy. Arbel H, et al. Proc Natl Acad Sci U S A, 2019 Jan 15. PMID 30598455, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: c17200622-17199217 mobile_element_type = transposon:H{}394

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic target inhibition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beaten path IIIc
    Names
    Beat-IIIC
    CG15138-PA
    CG15138-PB
    beat-IIIc-PA
    beat-IIIc-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      17187637..17260734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135986.3 → NP_609830.2  beaten path IIIc, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609830.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJF1
      Related
      FBpp0080525
      Conserved Domains (3) summary
      cd00096
      Location:42 → 127
      Ig; Immunoglobulin domain
      smart00410
      Location:33 → 127
      IG_like; Immunoglobulin like
      cl11960
      Location:140 → 219
      Ig; Immunoglobulin domain

    2. NM_165209.2 → NP_724042.1  beaten path IIIc, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY13, Q9VJE9
      Related
      FBpp0080524
      Conserved Domains (3) summary
      cd00096
      Location:42 → 127
      Ig; Immunoglobulin domain
      smart00410
      Location:33 → 127
      IG_like; Immunoglobulin like
      cl11960
      Location:140 → 219
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SY13 Q8SY13
    Q95UI2 Q95UI2
    Q9VJF1 Q9VJF1

    Gene LinkOut

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