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    edin elevated during infection [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317900, updated on 9-Dec-2024

    Summary

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    Official Symbol
    edinprovided by FlyBase
    Official Full Name
    elevated during infectionprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052185
    Locus tag
    Dmel_CG32185
    See related
    AllianceGenome:FB:FBgn0052185
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32185; Dmel\CG32185; Edin
    Summary
    Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and humoral immune response. Located in extracellular space. Is expressed in embryonic/larval hemolymph. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See edin in Genome Data Viewer
    Location:
    74D1-74D1; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17494880..17495300)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17487980..17488400)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene quijote Neighboring gene Organic anion transporting polypeptide 74D Neighboring gene U4-U6 small nuclear riboprotein factor 60K Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Intruding Wolbachia Strain from the Moth Fails to Establish Itself in the Fruit Fly Due to Immune and Exclusion Reactions. Liu XC, et al. Curr Microbiol, 2020 Sep. PMID 32506239
    2. Edin Expression in the Fat Body Is Required in the Defense Against Parasitic Wasps in Drosophila melanogaster. Vanha-Aho LM, et al. PLoS Pathog, 2015 May. PMID 25965263, Free PMC Article
    3. Amendment of Altered Immune Response by Curcumin in Drosophila Model of Huntington's Disease. Dhankhar J, et al. J Huntingtons Dis, 2023. PMID 37781812
    4. Transmission of the wMel Wolbachia strain is modulated by its titre and by immune genes in Drosophila melanogaster (Wolbachia density and transmission). Liu XC, et al. J Invertebr Pathol, 2021 May. PMID 33882275
    5. Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection. Anderl I, et al. PLoS Pathog, 2016 Jul. PMID 27414410, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in humoral immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    elevated during infection
    Names
    CG32185-PA
    edin-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17494880..17495300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168735.2 → NP_730278.1  elevated during infection [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ02, Q8IQR7
      Related
      FBpp0074940
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQR7 Q8IQR7

    Gene LinkOut

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