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    CG9727 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40794, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9727provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037445
    Locus tag
    Dmel_CG9727
    See related
    AllianceGenome:FB:FBgn0037445
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9727
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in organism. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and severe combined immunodeficiency. Orthologous to human RFX5 (regulatory factor X5) and RFX7 (regulatory factor X7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9727 in Genome Data Viewer
    Location:
    83E7-83E8; 3-47.5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6449944..6456676, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2275666..2282398, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Dementin Neighboring gene long non-coding RNA:CR44017 Neighboring gene grappa Neighboring gene mir-9375 stem loop Neighboring gene Zinc-finger protein Neighboring gene neurochondrin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatial expression of transcription factors in Drosophila embryonic organ development. Hammonds AS, et al. Genome Biol, 2013 Dec 20. PMID 24359758, Free PMC Article
    2. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
    3. Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N, et al. Development, 2014 Oct. PMID 25294943, Free PMC Article
    4. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article
    5. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9727-PA
    CG9727-PB
    CG9727-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6449944..6456676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275389.1 → NP_001262318.1  uncharacterized protein Dmel_CG9727, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262318.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI23
      Conserved Domains (1) summary
      pfam02257
      Location:307 → 383
      RFX_DNA_binding; RFX DNA-binding domain

    2. NM_141399.3 → NP_649656.1  uncharacterized protein Dmel_CG9727, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649656.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI23
      Related
      FBpp0081227
      Conserved Domains (1) summary
      pfam02257
      Location:307 → 383
      RFX_DNA_binding; RFX DNA-binding domain

    3. NM_001275388.1 → NP_001262317.1  uncharacterized protein Dmel_CG9727, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262317.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGM5
      Conserved Domains (1) summary
      pfam02257
      Location:307 → 383
      RFX_DNA_binding; RFX DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGM5 A0A0B4KGM5
    Q9VI23 Q9VI23

    Gene LinkOut

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