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    Dlip2 Dorsal interacting protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40579, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dlip2provided by FlyBase
    Official Full Name
    Dorsal interacting protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0040466
    Locus tag
    Dmel_CG9771
    See related
    AllianceGenome:FB:FBgn0040466
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9771; dip2; Dip2; DIP2; dmDIP2; Dmel\CG9771; sip4
    Summary
    Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dlip2 in Genome Data Viewer
    Location:
    82C5-82C5; 3-47.1 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4644649..4645655, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (470371..471377, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene stable intronic sequence RNA CR46358 Neighboring gene uncharacterized protein Neighboring gene Mediator complex subunit 31 Neighboring gene nuclease slx1 Neighboring gene antisense RNA:CR44155 Neighboring gene ripped pocket Neighboring gene Karyopherin beta 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of Septin 4, the Drosophila homologue of human CDCrel-1, is toxic for dopaminergic neurons. Muñoz-Soriano V, et al. Eur J Neurosci, 2007 Dec. PMID 18028112
    2. A functional interaction between dorsal and components of the Smt3 conjugation machinery. Bhaskar V, et al. J Biol Chem, 2000 Feb 11. PMID 10660560
    3. Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila. Shih HP, et al. J Cell Sci, 2002 Mar 15. PMID 11884525
    4. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Roussigne M, et al. Trends Biochem Sci, 2003 Feb. PMID 12575992
    5. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Tsubouchi A, et al. Curr Biol, 2012 Nov 20. PMID 23103192, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This indicates that Septin 4 accumulation is toxic for DA neurons and suggests that Septin 4 could be a genuine substrate of Drosophila Parkin.
      Title: Overexpression of Septin 4, the Drosophila homologue of human CDCrel-1, is toxic for dopaminergic neurons.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    dorsal interacting protein 2
    Names
    CG9771-PA
    Dlip2-PA
    septin interacting protein 4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4644649..4645655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079500.4 → NP_524224.2  dorsal interacting protein 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524224.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NHV6, Q9VN42
      Related
      FBpp0078533
      Conserved Domains (1) summary
      pfam05485
      Location:5 → 83
      THAP; THAP domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NHV6 Q9NHV6
    Q9VN42 Q9VN42

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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