mIF3 mitochondrial translation initiation factor 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mIF3provided by FlyBase
Official Full Name: mitochondrial translation initiation factor 3provided by FlyBase
Primary source: FLYBASE:FBgn0033712
Locus tag: Dmel_CG13163
See related: AllianceGenome:FB:FBgn0033712
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13163; Dmel\CG13163
Summary: Predicted to enable ribosomal small subunit binding activity and translation initiation factor activity. Predicted to be involved in mitochondrial translational initiation and ribosome disassembly. Predicted to be active in mitochondrion. Is expressed in adult head and adult heart. Orthologous to human MTIF3 (mitochondrial translational initiation factor 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (12321238..12322797)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (8208743..8210302)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

EGR1-Driven METTL3 Activation Curtails VIM-Mediated Neuron Injury in Epilepsy.
Title: EGR1-Driven METTL3 Activation Curtails VIM-Mediated Neuron Injury in Epilepsy.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ribosomal small subunit binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables ribosome binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation factor activity, RNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in mitochondrial translational initiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial translational initiation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in ribosome disassembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome disassembly	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain