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    CG4914 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39597, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4914provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036436
    Locus tag
    Dmel_CG4914
    See related
    AllianceGenome:FB:FBgn0036436
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4914; SP39
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including cuboidal/columnar epithelium; embryonic hindgut; embryonic precursor of adult hindgut; embryonic ventral epidermis; and foregut primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4914 in Genome Data Viewer
    Location:
    70E7-70E7; 3-42 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14674538..14678147, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14667638..14671247, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:initiator Methionine-CAT 1-4 Neighboring gene transfer RNA:initiator Methionine-CAT 1-5 Neighboring gene omega Neighboring gene Dynein axonemal assembly factor 6 Neighboring gene goddard

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. Ni JQ, et al. Genes Dev, 2006 Jul 15. PMID 16816001, Free PMC Article
    2. Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Klebes A, et al. Development, 2005 Aug. PMID 16077094
    3. Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. Firth LC, et al. Dev Biol, 2007 Jul 15. PMID 17553483, Free PMC Article
    4. Trachealess (Trh) regulates all tracheal genes during Drosophila embryogenesis. Chung S, et al. Dev Biol, 2011 Dec 1. PMID 21963537, Free PMC Article
    5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4914-PA
    NP_648711.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      14674538..14678147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140454.3 → NP_648711.1  uncharacterized protein Dmel_CG4914 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648711.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95R91, Q9VUG2
      Related
      FBpp0075456
      Conserved Domains (2) summary
      smart00020
      Location:127 → 360
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:128 → 363
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VUG2 Q9VUG2

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