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    CG3065 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37818, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3065provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034946
    Locus tag
    Dmel_CG3065
    See related
    AllianceGenome:FB:FBgn0034946
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3065
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; embryonic ventral epidermis; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3065 in Genome Data Viewer
    Location:
    60A14-60A15; 2-105 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23970305..23972233)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19857828..19859756)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene orange Neighboring gene uncharacterized protein Neighboring gene morula Neighboring gene Protein phosphatase 1 regulatory subunit 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks. Marbach D, et al. Genome Res, 2012 Jul. PMID 22456606, Free PMC Article
    2. δ-Aminolevulinate synthase is required for apical transcellular barrier formation in the skin of the Drosophila larva. Shaik KS, et al. Eur J Cell Biol, 2012 Mar. PMID 22293958
    3. The anaphase promoting complex/cyclosome is required during development for modified cell cycles. Kashevsky H, et al. Proc Natl Acad Sci U S A, 2002 Aug 20. PMID 12169670, Free PMC Article
    4. An Sp1/KLF binding site is important for the activity of a Polycomb group response element from the Drosophila engrailed gene. Brown JL, et al. Nucleic Acids Res, 2005. PMID 16155187, Free PMC Article
    5. Mammalian SP/KLF transcription factors: bring in the family. Suske G, et al. Genomics, 2005 May. PMID 15820306

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3065-PA
    CG3065-PB
    CG3065-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23970305..23972233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138017.2 → NP_611861.1  uncharacterized protein Dmel_CG3065, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611861.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2MGN0, Q5BIG5
      Related
      FBpp0072064
      Conserved Domains (4) summary
      COG5048
      Location:99 → 400
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:111 → 133
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:346 → 368
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:155 → 180
      zf-H2C2_2; Zinc-finger double domain

    2. NM_166643.2 → NP_726393.1  uncharacterized protein Dmel_CG3065, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726393.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BIG5, Q8MLQ3
      Related
      FBpp0072062
      Conserved Domains (4) summary
      COG5048
      Location:77 → 378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:89 → 111
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:324 → 346
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:133 → 158
      zf-H2C2_2; Zinc-finger double domain

    3. NM_166642.2 → NP_726392.1  uncharacterized protein Dmel_CG3065, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726392.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2MGN0, Q5BIG5
      Related
      FBpp0072063
      Conserved Domains (4) summary
      COG5048
      Location:99 → 400
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:111 → 133
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:346 → 368
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:155 → 180
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2MGN0 Q2MGN0
    Q5BIG5 Q5BIG5
    Q86LE8 Q86LE8
    Q8MLQ3 Q8MLQ3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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