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    CG1662 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32296, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1662provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030481
    Locus tag
    Dmel_CG1662
    See related
    AllianceGenome:FB:FBgn0030481
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1662
    Summary
    Predicted to enable monoatomic ion channel activity. Predicted to be involved in mitochondrial ribosome assembly and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in organism. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1662 in Genome Data Viewer
    Location:
    11F1-11F1; 1-43 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13387563..13389332)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13281596..13283365)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Tim9a Neighboring gene Yippee Neighboring gene long non-coding RNA:CR44620 Neighboring gene long non-coding RNA:CR44621

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Drosophila model of the neurological symptoms in Mpv17-related diseases. Kodani A, et al. Sci Rep, 2022 Dec 31. PMID 36587049, Free PMC Article
    2. Drosophila Mpv17 forms an ion channel and regulates energy metabolism. Corrà S, et al. iScience, 2023 Oct 20. PMID 37810222, Free PMC Article
    3. Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Whitaker R, et al. Aging (Albany NY), 2014 May. PMID 24864304, Free PMC Article
    4. Characteristics of genes up-regulated and down-regulated after 24 h starvation in the head of Drosophila. Fujikawa K, et al. Gene, 2009 Oct 1. PMID 19573582
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial ribosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1662-PA
    CG1662-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13387563..13389332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132655.3 → NP_572883.1  uncharacterized protein Dmel_CG1662, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572883.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9YH55, Q9VYD6
      Related
      FBpp0073607
      Conserved Domains (1) summary
      pfam04117
      Location:170 → 234
      Mpv17_PMP22; Mpv17 / PMP22 family

    2. NM_001298280.1 → NP_001285209.1  uncharacterized protein Dmel_CG1662, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285209.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9YH55, Q9VYD6
      Conserved Domains (1) summary
      pfam04117
      Location:170 → 234
      Mpv17_PMP22; Mpv17 / PMP22 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYD6 Q9VYD6

    Gene LinkOut

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