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    CG31954 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33572, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31954provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051954
    Locus tag
    Dmel_CG31954
    See related
    AllianceGenome:FB:FBgn0051954
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3229; Dmel\CG31954; SP107
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS3P2 (PRSS3 pseudogene 2); PRSS1 (serine protease 1); and PRSS2 (serine protease 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31954 in Genome Data Viewer
    Location:
    23F6-23F6; 2-10 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3509058..3510102, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3509058..3510102, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene timeless Neighboring gene snoRNA:Orphan CD box 16 Neighboring gene long non-coding RNA:CR45299 Neighboring gene antisense RNA:CR45300 Neighboring gene Leucyl-tRNA synthetase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31954-PA
    NP_722915.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3509058..3510102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164543.4 → NP_722915.1  uncharacterized protein Dmel_CG31954 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQ10
      Related
      FBpp0077252
      Conserved Domains (2) summary
      smart00020
      Location:50 → 271
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:51 → 274
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQ10 Q8IQ10

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