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    CG8635 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35850, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8635provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033317
    Locus tag
    Dmel_CG8635
    See related
    AllianceGenome:FB:FBgn0033317
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8635
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytosol. Is expressed in several structures, including embryonic/larval midgut primordium; epithelial tube; gut section; larval muscle cell; and mesoderm. Orthologous to human ZC3H15 (zinc finger CCCH-type containing 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8635 in Genome Data Viewer
    Location:
    44D5-44D5; 2-59 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8630207..8631962, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4517712..4519467, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene beta-1,3-Galactosyltransferase II Neighboring gene Gle1 RNA export mediator Neighboring gene long non-coding RNA:CR44281 Neighboring gene patched Neighboring gene Acyl-CoA synthetase long-chain Neighboring gene Ubiquinol-cytochrome c reductase 11 kDa subunit-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD. Park J, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34551427, Free PMC Article
    2. Drosophila Gut Immune Pathway Suppresses Host Development-Promoting Effects of Acetic Acid Bacteria. Lee J, et al. Mol Cells, 2023 Oct 31. PMID 37853687, Free PMC Article
    3. Highly effective proximate labeling in Drosophila. Zhang B, et al. G3 (Bethesda), 2021 May 7. PMID 33724396, Free PMC Article
    4. In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor. Baker FC, et al. Development, 2021 Nov 15. PMID 35020877, Free PMC Article
    5. SUMO-Enriched Proteome for Drosophila Innate Immune Response. Handu M, et al. G3 (Bethesda), 2015 Aug 18. PMID 26290570, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8635-PA
    CG8635-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8630207..8631962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136557.3 → NP_610401.1  uncharacterized protein Dmel_CG8635, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610401.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JWR9
      UniProtKB/TrEMBL
      A0A0B4LEV3
      Related
      FBpp0087806
      Conserved Domains (3) summary
      smart00356
      Location:94 → 120
      ZnF_C3H1; zinc finger
      COG5252
      Location:1 → 314
      COG5252; Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function prediction only]
      pfam16543
      Location:219 → 314
      DFRP_C; DRG Family Regulatory Proteins, Tma46

    2. NM_001299273.1 → NP_001286202.1  uncharacterized protein Dmel_CG8635, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286202.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JWR9
      UniProtKB/TrEMBL
      A0A0B4LEV3
      Conserved Domains (3) summary
      smart00356
      Location:94 → 120
      ZnF_C3H1; zinc finger
      COG5252
      Location:1 → 314
      COG5252; Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function prediction only]
      pfam16543
      Location:219 → 314
      DFRP_C; DRG Family Regulatory Proteins, Tma46
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LEV3 A0A0B4LEV3
    Q7JWR9.1 Q7JWR9

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