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    mRpL11 mitochondrial ribosomal protein L11 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41757, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRpL11provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L11provided by FlyBase
    Primary source
    FLYBASE:FBgn0038234
    Locus tag
    Dmel_CG3351
    See related
    AllianceGenome:FB:FBgn0038234
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE67638; CG3351; Dmel\CG3351; L11; rpl-11
    Summary
    Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in adult head. Orthologous to human MRPL11 (mitochondrial ribosomal protein L11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mRpL11 in Genome Data Viewer
    Location:
    88C3-88C3; 3-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14511838..14512691)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10337560..10338413)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44177 Neighboring gene HTRA2-related serine protease Neighboring gene uncharacterized protein Neighboring gene Phosphodiesterase 6 Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 313a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin. Tain LS, et al. Cell Death Differ, 2009 Aug. PMID 19282869, Free PMC Article
    2. Chronological requirements of TDP-43 function in synaptic organization and locomotive control. Romano G, et al. Neurobiol Dis, 2014 Nov. PMID 25088713
    3. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Ishizuka A, et al. Genes Dev, 2002 Oct 1. PMID 12368261, Free PMC Article
    4. TRPM channels mediate zinc homeostasis and cellular growth during Drosophila larval development. Georgiev P, et al. Cell Metab, 2010 Oct 6. PMID 20889130
    5. TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization. Godena VK, et al. PLoS One, 2011 Mar 11. PMID 21412434, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein L11
    Names
    CG3351-PA
    mRpL11-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14511838..14512691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079627.3 → NP_524351.1  mitochondrial ribosomal protein L11 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524351.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VFJ2
      Related
      FBpp0082412
      Conserved Domains (2) summary
      cd00349
      Location:24 → 157
      Ribosomal_L11; Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal ...
      smart00649
      Location:24 → 158
      RL11; Ribosomal protein L11/L12
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFJ2.1 Q9VFJ2

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